Results 51 to 60 of about 695,537 (301)

Regulation of anti-tumour effects of Paris polyphylla saponins via ROS: molecular mechanisms and therapeutic potentials

Frontiers in Pharmacology
Reactive oxygen species (ROS) exhibit a dual regulatory role in cancer biology. While moderate ROS levels promote tumorigenesis via DNA mutagenesis, excessive ROS accumulation induces cancer cell death through oxidative stress. Therefore, ROS homeostasis
Jia Liu, Yongping Mu, Yongping Mu, Ke Qi, Jiayi Li, Yang Hu   +5 more
doaj   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

Ribosome biogenesis in osteoarthritis: mechanisms and therapeutic potential

Journal of Translational Medicine
Background Ribosomes are the core machinery for cellular protein synthesis, and defects in their biogenesis have been confirmed to be closely associated with various diseases.
Zewen Xu, Zhiwei Pei, Haobo Yang, Shanjie Guo, Qiang Li, Liuchang Jiang, Jing Wang, Leipeng Wang, Dexin Liu, Xuanyin Chen, Baoxin Zhang, Ting Hao   +11 more
doaj   +1 more source

The complete mitochondrial DNA analyses of Inner Mongolia Cashmere goat type of Erlangshan species

Mitochondrial DNA. Part B. Resources, 2018
Inner Mongolia Cashmere goat is evolved from Mongolia goat in long-term breeding, as a source of high-quality cashmere, Inner Mongolia Cashmere goat type of Erlangshan is famous in the world.
Yuhao Ma, Rui Su, Yixing Fan, Xian Qiao, Xiaokai Li, Lei Zhang, Jinquan Li   +6 more
doaj   +1 more source

Electropulse‐Driven Dislocation Evolution in Sub‐10 nm Metallic Nanocrystals

Advanced Science, EarlyView.
Atomic‐scale TEM imaging reveals how nanosecond electropulses drive dislocation evolution in sub‐10 nm metallic nanocrystals. Enhanced electron scattering at structural heterogeneities nucleates dislocation loops and dipoles, which then repeatedly interact and annihilate, causing dislocation density fluctuations or structural disordering.
Youran Hong, Xiaoyu Zhai, Xing Li, Xinfang Zhang, Kexing Song, Ze Zhang, Jiangwei Wang   +6 more
wiley   +1 more source

Comprehensive landscape of cell death mechanisms: from molecular cross-talk to therapeutic innovation in oncology

Frontiers in Cell and Developmental Biology
Cell death, or programmed cellular termination, represents a fundamental biological phenomenon crucial for maintaining organismal homeostasis. Traditionally conceptualized as a passive terminal state associated with inflammatory responses and elimination
Ke Qi, Yongping Mu, Yongping Mu, Yang Hu, Jiayi Li, Jia Liu   +5 more
doaj   +1 more source

Dietary Artemisia ordosica extract alleviating immune stress in broilers exposed to lipopolysaccharide

Italian Journal of Animal Science, 2017
This study was conducted to investigate the effect of Artemisia ordosica extract (AOE) on broilers challenged with lipopolysaccharide (LPS). 96 one-day-old Arbour Acres broilers were assigned in 2 × 2 factorial design, including two dietary treatments (0
Kun Li, Pengfei Zhang, Binlin Shi, Junling Su, Yuanxi Yue, Manman Tong, Sumei Yan   +6 more
doaj   +1 more source

The Lao Ho in Inner Mongolia [PDF]

The Geographical Journal, 1907
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openaire   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

Engineering Thermal Cross-Linking in Nanofiltration Membranes for Efficient Nicotine Extraction from Tobacco Extract

Membranes
Tobacco extract contains numerous valuable components, among which nicotine possesses significant potential for high-value applications despite its well-known health risks.
He Du, Xinyuan Wang, Baodan Na, Yajun Ye, Yuemei Qiao, Linda Li, Ye Tian, Xiaoping Ning, Zhigang Wang, Xingquan Zhao, Chen Chen   +10 more
doaj   +1 more source