Results 51 to 60 of about 289,909 (310)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Inner Product Spaces

, 1997
In making the definition of a vector space, we generalized the linear structure (addition and scalar multiplication) of R2 and R3.
openaire   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Comparative mitogenomics reveals evolutionary drivers of Strongyloidea nematodes dwelling in gastrointestinal tract

BMC Genomics
Background The nematode superfamily Strongyloidea represents a prevalent group of gastrointestinal parasites in ruminants and livestock, posing substantial veterinary and economic burdens worldwide.
Junyan Li, Xiaochao Zhao, Pengwei Xu, Juan Lai, Gaowa Gong, Penglong Wang, Yanni Zhang, Xuerou Chen, Fang Guo, Xiaomin Wang, Yongfeng Liu, Xiaoping Luo   +11 more
doaj   +1 more source

Jamming decision under condition of incomplete jamming rule library

The Journal of Engineering, 2019
To solve the problem of the low rate of template matching (TM) jamming decision method under the incomplete jamming rule library condition in traditional electronic warfare, a clustering and resampling – support vector machine (CRS-SVM) jamming decision ...
Qiang Xing, Weigang Zhu, Zhou Chi, Guangyong Zheng   +3 more
doaj   +1 more source

Hypersurfaces in the general inner product spaces [PDF]

Journal of Hyperstructures, 2017
Let A be a symmetric positive definite (n+ 1)×(n+ 1) real matrix for n ≥ 1 and S ∈ R n+1 be a hypersurface. We are supposed to determine the tangent space TpS in an arbitrary point p ∈ S in the case that the whole space R n+1 admits the inner product ...
Ali Parsian
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Characterising gut microbiome dysbiosis in diarrhoea calves from multiple farms in Inner Mongolia using 16S and metagenomics

Microbiome
Background The pathogenesis of neonatal calf diarrhoea (NCD), a critical disease that contributes to neonatal mortality in calves, remains nebulous. Results Inner Mongolia, a key region for cattle farming in China, was selected as a study area to provide
Junyan Li, Xin Zhang, Xiaochao Zhao, Gaowa Gong, Jian Li, Baolige Dalai, Ziran Mo, Xiaojing Xu, Xiaoqing Jia, Yaning Li, Juan Lai, Penglong Wang, Lei Sun, Yongfeng Liu, Xiaoping Luo   +14 more
doaj   +1 more source

Further Inequalities for Sequences and Power Series of Operators in Hilbert Spaces Via Hermitian Forms

Moroccan Journal of Pure and Applied Analysis, 2016
By the use of some inequalities for nonnegative Hermitian forms some new inequalities for sequences and power series of bounded linear operators in complex Hilbert spaces are established.
Dragomir S. S.
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source