Results 71 to 80 of about 213,036 (304)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Their Voices Matter: Perceptions held by Black Males Regarding their Transition Planning and Postsecondary Outcomes [PDF]

, 2018
This qualitative study examined the perceptions of Black males identified as having a specific learning disability, intellectual disability, or emotional disturbance about their high school transition planning as well as their postsecondary outcomes. The
Payne, ReJeana
core  

Transition matrix of wetlands and non-wetlands in Inner Mongolia during 1993–2013 (in %).

, 2019
Transition matrix of wetlands and non-wetlands in Inner Mongolia during 1993–2013 (in %).
Lixin Wang (343011), Yi Zhuo (3778381), Ying Zheng (170527), Cunzhu Liang (728892), Zhiyong Li (47765), Huamin Liu (6852678)   +5 more
core   +1 more source

Accretion on to Magnetic White Dwarfs

EPJ Web of Conferences, 2014
The Magnetic Cataclysmic Variables (MCVs) are close interacting binaries where mass is transferred from a late type secondary star to a magnetic white dwarf.
Wickramasinghe Dayal
doaj   +1 more source

TRANSITION DENSITY AND PRESSURE AT THE INNER EDGE OF NEUTRON STAR CRUSTS [PDF]

International Journal of Modern Physics E, 2010
Using the nuclear symmetry energy that has been recently constrained by the isospin diffusion data in intermediate-energy heavy ion collisions, we have studied the transition density and pressure at the inner edge of neutron star crusts, and they are found to be 0.040 fm -3 ≤ ρt ≤ 0.065 fm -3 and 0.01 MeV / fm 3 ≤ Pt ≤ 0.26 MeV / fm 3, respectively ...
Xu, Jun, Ko, Che Ming, Chen, Lie-Wen, Li, Bao-an, Ma, Hong-Ru   +4 more
openaire   +2 more sources

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Thermodynamic stability of Fe/O solid solution at inner-core conditions

, 2000
We present a new technique which allows the fully ab initio calculation of the chemical potential of a substitutional impurity in a high-temperature crystal, including harmonic and anharmonic lattice vibrations.
Price, GD, Alfe D, Gillan MJ, Price GD, Alfè, A, Gillan, MJ   +5 more
core   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source