Results 61 to 70 of about 256,764 (360)

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

Transformation of Melodrama in Turkish Cinema from Yeşilçam to the Present: The Films Innocence and Destiny

open access: yesSelçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi
Melodramas are dramatic works of art where the detailed character studies dominate the plot. The dialogues used in melodramas are generally emotional, and the characters are often portrayed in stereotypical forms.
Kemal Çelik
doaj   +1 more source

Unless Someone Like You Cares a Whole Awful Lot: Apocalypse as Children’s Entertainment [PDF]

open access: yes, 2017
This article explores an unusual subset of children’s narrative, the apocalyptic environmentalist text, and argues that such texts perform the perverse ideological work of shifting blame for ecological crisis from its perpetrators (the parents ...
Canavan, Gerry
core   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

The Influence of Regret Proneness, Evidence Strengthening, and Perceived Responsibility on Verdict Preference [PDF]

open access: yes, 2011
In the present study, we investigated perceived responsibility, evidence strengthening, and defendant gender in the context of a criminal trial involving DNA.
Oglesby, Stephanie L.
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Judging Innocence [PDF]

open access: yes, 2008
This empirical study examines for the first time how the criminal justice system in the United States handled the cases of people who were subsequently found innocent through postconviction DNA testing.
Garrett, Brandon L.
core   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Tragic Innocence in Philip Roth’s American Pastoral

open access: yesRomanian Journal of English Studies, 2012
American Pastoral is not only an elegiac fictional biography, but an in-depth analysis of the demise of the American dream in the context of post-war social and cultural mutations.
Glăvan Gabriela
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

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