Results 71 to 80 of about 256,764 (360)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Trying Cases in the Media: A Comparative Overview [PDF]

open access: yes, 2008
The essay deals with the problem of media impact on ongoing trials. In particular, it proposes a taxonomy of three comparative models of governance (traditional common law approach; US approach; Continental European approach) and makes a case for the ...
Resta, Giorgio
core   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

THE WAY TO GRACE: TERRENCE MALICK’S ECOTHEOLOGICAL VISION IN THE TREE OF LIFE [PDF]

open access: yesUniversity of Bucharest Review. Literary and Cultural Studies Series, 2012
Terrence Malick’s fifth and most experimental film The Tree of Life provides a fertile ground for exploring the various facets of Nature, along with the questions these raise and the implications they carry for understanding our fraught relationships ...
Laura Savu
doaj  

The Presumption of Innocence as a Counterfactual Principle

open access: yesUtrecht Law Review, 2016
This article’s primary aim is to highlight the essentially critical potential of the presumption of innocence, as well as the need for this critical potential to be duly recognized.
Ferry de Jong, Leonie van Lent
doaj   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

The innocence of Jacques-Pierre Brissot [PDF]

open access: yes, 2003
Even during his lifetime, the French revolutionary Girondin leader Jacques-Pierre Brissot de Warville's reputation was tarnished by allegations that, before 1789, he was a swindler, police spy, and political pornographer.
Burrows, S.
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Chamber Music Concert, March 31, 1983 [PDF]

open access: yes, 1983
This is the concert program of Chamber Music Concert on Thursday, March 31, 1983 at 1:00 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed were Four Miniatures for Woodwind Trio by John Cheetham, Quartet in G major, K.
School of Music, Boston University
core  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

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