Results 71 to 80 of about 260,584 (356)
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
The Presumption of Innocence as a Counterfactual Principle
This article’s primary aim is to highlight the essentially critical potential of the presumption of innocence, as well as the need for this critical potential to be duly recognized.
Ferry de Jong, Leonie van Lent
doaj +1 more source
Trying Cases in the Media: A Comparative Overview [PDF]
The essay deals with the problem of media impact on ongoing trials. In particular, it proposes a taxonomy of three comparative models of governance (traditional common law approach; US approach; Continental European approach) and makes a case for the ...
Resta, Giorgio
core +1 more source
An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino +7 more
wiley +1 more source
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
Chamber Music Concert, March 31, 1983 [PDF]
This is the concert program of Chamber Music Concert on Thursday, March 31, 1983 at 1:00 p.m., at the Concert Hall, 855 Commonwealth Avenue. Works performed were Four Miniatures for Woodwind Trio by John Cheetham, Quartet in G major, K.
School of Music, Boston University
core
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Pretpostavka nevinosti okrivljenog kao element prava na pravično suđenje [PDF]
Although the presumption of innocence has its roots in the rational criminal procedure of the ancient times, it should still be seen as a result of the modern criminal procedure system, i.e.
Drago Radulović
doaj +1 more source

