Results 151 to 160 of about 458,507 (263)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Fondo Nacional para el Financiamiento de la Ciencia, la Tecnología y la Innovación-FRANCISCO JOSE DE CALDAS -

El Fondo de Financiamiento para la Ciencia, la Tecnología y la Innovación es un instrumento financiero que surge a partir de la Ley 1286 de 2009 y que le permite a COLCIENCIAS desarrollar un mecanismo flexible para financiar la CTI, integrando Recursos ...
Departamento Administrativo de Ciencia, Tecnología e Innovación - Colciencias
core  

A cost‐effective DNA extraction protocol for long‐read sequencing in non‐model plants

Applications in Plant Sciences, EarlyView.
Abstract Premise Third‐generation sequencing has revolutionized genomics, enabling in‐depth analysis of genome sequence, structure, and epigenetic features. Yet, extracting high‐quality DNA for long‐read sequencing remains a bottleneck—particularly in non‐model plants, such as mature trees growing in natural environments, which often contain abundant ...
Sofia Gaischuk, Cintia F. Marchetti, Ezequiel Petrillo, Fernando A. Rabanal, Detlef Weigel, Nicolás Bellora, M. Verónica Arana   +6 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

Hepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro, Rut Espinosa‐Sotelo, Eva Crosas‐Molist, Macarena Herranz‐Itúrbide, Daniel Caballero‐Díaz, Ania Alay, Xavier Solé, Emilio Ramos, Teresa Serrano, María L. Martínez‐Chantar, Ulla G. Knaus, José M. Cuezva, Antonio Zorzano, Esther Bertran, Isabel Fabregat   +14 more
wiley   +1 more source

La concentración de la oferta como fuente de innovación de los nuevos negocios: el estudio de un caso en el sector de la automoción en Cataluña

Revista Galega de Economía, 2014
La innovación es un elemento clave para la creación y desarrollo de empresas exitosas, sobre todo para aquellos negocios que se integran en sectores maduros o complejos. En el presente trabajo, adoptando la metodología cualitativa de estudio de casos, se analizan los aspectos innovadores que han definido y desencadenado la creación de un nuevo ...
openaire   +1 more source

Diez casos exitosos de innovación tecnológica

Diez casos exitosos de innovación tecnológica es una publicación de Colciencias que presenta la experiencia de igual número de industrias colombianas e iberoamericanas cuando decidieron, de una vez por todas, iniciar el proceso interno de innovación ...
Colombia. Departamento Administrativo de Ciencia, Tecnología e Innovación. Colciencias
core  

Impedance Spectroscopy of Bifurcation Oscillations in S‐Type Self‐Oscillatory Devices

Advanced Physics Research, EarlyView.
Impedance spectroscopy (IS) reveals stability regimes and bifurcation dynamics in S‐type self‐oscillatory devices. By linking nonlinear control theory with frequency‐domain measurements, experimental signatures of oscillations, entrainment, and phase locking are directly identified.
Gonzalo Rivera‐Sierra, Roberto Fenollosa, Jenifer Rubio‐Magnieto, Nripan Mathews, Si En Ng, Juan Bisquert   +5 more
wiley   +1 more source

Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression

Hepatology, EarlyView., 2022
Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández, Naroa Goikoetxea‐Usandizaga, David Porras, María Victoria García‐Mediavilla, Miren Bravo, Marina Serrano‐Maciá, Jorge Simón, Teresa C. Delgado, Sofía Lachiondo‐Ortega, Susana Martínez‐Flórez, Óscar Lorenzo, Mercedes Rincón, Marta Varela‐Rey, Leticia Abecia, Héctor Rodríguez, Juan Anguita, Esther Nistal, María Luz Martínez‐Chantar, Sonia Sánchez‐Campos   +18 more
wiley   +1 more source

New techniques for old bones: Morphometric and diffeomorphometric analysis of the bony labyrinth of the Reilingen and Ehringsdorf Neandertals

The Anatomical Record, EarlyView.
Abstract Neandertals are known to possess very distinctive traits in their bony labyrinth morphology, such as an inferiorly positioned posterior canal and a very low number of turns in the cochlea. Hence, the inner ear has been often used to assess the Neandertal status of fragmentary fossils.
Alessandro Urciuoli, Julia Diez‐Valero, Ignacio Martínez, Rolf Quam, Brian A. Keeling, Nicole M. Webb, Mercedes Conde‐Valverde   +6 more
wiley   +1 more source

Cementum Attachment Protein-Derived Peptides Modulate Brushite and Calcium Oxalate Crystallization In Vitro. [PDF]

J Pept Sci
Mimila-Cortes A, Arenas-Alatorre J, Jiménez-Duran K, González-Andrade M, Hoz-Rodríguez L, Santana-Vázquez M, Ramírez-González LF, Castro-López KI, Arzate H, Montoya-Ayala G.   +9 more
europepmc   +1 more source