Results 31 to 40 of about 5,165,706 (279)

Business Models for the Internet of Services: State of the Art and Research Agenda

open access: yesFuture Internet, 2022
The relevance of the Internet of Services (IoS) comes from the global reach of the Internet into everyone’s home and daily activities and from the move from a manufacturing-based economy to a service-based economy.
Jacqueline Zonichenn Reis   +3 more
doaj   +1 more source

Managing innovation in English language education, state of the art review. [PDF]

open access: yes, 2009
Innovation in English language education (ELE) has become a major ‘growth area’ in recent years. At the same time, an ELE innovation management literature has also developed, based on insights from innovation theory and their application, both from ...
Waters, Alan
core   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

open access: yesFEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera   +4 more
wiley   +1 more source

Enjoying the Heat? Co-Creation of Stakeholder Benefits and Sustainable Energy Development within Projects in the Geothermal Sector

open access: yesEnergies, 2022
Analysis of the sustainability implications of the geothermal industry has tended to take a high-level or systemic overview of national performance rather than deeper, stakeholder-focused investigations.
David Cook   +2 more
doaj   +1 more source

Reflexivity and flexibility: Complementary routes to innovation? [PDF]

open access: yes, 2016
Flexibility and reflexivity are essential processes for organisational innovation. The aim of the paper is to investigate their concurrent and interactive contribution in enhancing two innovation outcomes (the organisational openness towards innovation ...
Aiken   +17 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

The mediation between participative leadership and employee exploratory innovation: Examining intermediate knowledge mechanisms [PDF]

open access: yes, 2019
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.We examine mediation effects of coworker knowledge sharing and absorptive capacity on the participative ...
Chang, Che-Yuan   +3 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Regional innovation case study review volume 2, 2007 - 2008 [PDF]

open access: yes, 2007
A continuation of Volume 1, this 'Case Study Review' showcases a collection of case studies that represent the range of innovation support products and services available in the ...
East Midlands Innovation
core   +1 more source

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