Results 51 to 60 of about 2,891,562 (358)
FEBS Letters, EarlyView.Tuberculosis remains a global health challenge and new therapeutic targets are required. Here, we characterized SseA, a sulfurtransferase from Mycobacterium tuberculosis involved in macrophage infection, and its interaction with the newly identified protein SufEMtb that activates SseA enzymatic activity.
Giulia Di Napoli +10 more
wiley +1 more source
Central problems in the management of innovation
, 1986 Innovation is defined as the development and implementation of new ideas by people who over time engage in transactions with others within an institutional order.
A. Ven
semanticscholar +1 more source
INNOVATIONS: Managing innovation and innovators
College & Research Libraries News, 1987 INNOVATIONS: Managing innovation and ...
openaire +3 more sources
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Journal of Open Innovation: Technology, Market and Complexity, 2020 It has become a burgeoning trend for the innovation paradigm to shift from producer-dominant to non-producer centric. Based on a critical review of the non-producer innovation literature, we identified several limitations of existing non-producer ...
Jin Chen, Linghui Han, Guannan Qu
doaj +1 more source
Strategic Decisions, 2019 WHAT IF YOU COULD AMPLIFY HYDRAULIC FORCE WITHOUT ADDING ANY EXTRA BULK TO YOUR VEHICLE? A GROUNDBREAKING INNOVATION ENABLES YOU TO DO JUST THAT, HELPING TO IMPROVE THE OVERALL EFFECTIVENESS OF ANY ...
Paolo Fontana, J. P. Todsen
semanticscholar +1 more source
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Innovation and new ways of working across sectors
Forced Migration Review, 2014 Humanitarian actors will have to adapt to a changing world but it will not be easy or straightforward. Operations are changing as a result of innovations which bring many improvements but also throw up challenges.
Erik Abild
doaj
USV Annals of Economics and Public Administration, 2022 With growing global actions toward sustainability, businesses have to align their course ensuring it as an outcome of their core business strategy. Businesses have to adapt this challenge and create opportunities to integrate sustainability in their ...
Managing knowledge and innovation for sustainable models of business: a systematic literature network analysis
doaj
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source