Results 51 to 60 of about 6,801,825 (368)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
ALPPS: Innovation for innovation's sake [PDF]
Surgery, 2016 HEPATIC RESECTION AND ABLATIVE PROCEDURES, which remain the mainstay treatment for patients with resectable colorectal liver metastases (CRLMs), can be facilitated by preoperative volumetric modulation when an insufficient liver remnant and/or diseased parenchyma are anticipated.
Jacques, Belghiti +2 more
openaire +2 more sources
FEBS Letters, EarlyView.Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang +5 more
wiley +1 more source
Assessing construction innovation: theoretical and practical perspectives [PDF]
, 2016 Innovation is key for productivity improvement and advancements in different sectors of the economy, including the construction sector. The criticism of the slow pace of innovation in construction industry may be unwarranted, considering the structure ...
Davis, Peter +3 more
core +3 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Leadership as an Enabler of Innovation Climate and Innovative Work Behavior in Indonesia’s Public Libraries [PDF]
, 2023 Dyah Puspitasari Srirahayu +2 more
openalex +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Innovating Firms and Aggregate Innovation [PDF]
Journal of Political Economy, 2002 We develop a parsimonious model of innovation to confront firmlevel evidence. It captures the dynamics of individual heterogeneous firms, describes the behavior of an industry with firm entry and exit, and delivers a general equilibrium model of technological change.
Klette, Tor Jakob, Kortum, Samuel
openaire +6 more sources
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
NATURAL BASES AND ARTISTIC MEANS OF MODERN ARTS AND CRAFTS OF DAGESTAN
Юг России: экология, развитие, 2016 The aim is to carry out a generalized analysis of the history of formation of a new artistic language in contemporary arts and crafts of Dagestan. An innovative search for applied artist has gained further development in a series of works of the leading ...
G. G. Gazimagomedov
doaj +1 more source