Results 61 to 70 of about 5,027,651 (300)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Organizational Factors and Intrapreneurial Competences

open access: yesInternational Journal of Innovation, 2013
This study analyzes the relationship between organizational factors and entrepreneurial competencies of coordinators of undergraduate courses in two community universities in Santa Catarina, Brazil.
Suzete Antonieta Lizote   +2 more
doaj   +1 more source

Innovation and Collective Entrepreneurship [PDF]

open access: yes, 2011
This paper examines different forms of innovation including social innovation, and why innovation and social innovation have become important themes in public policy in a context of the increasing and diverse demands on welfare regimes, and in an era of ...
Spear, Roger
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Marketing communications model for innovation networks

open access: yesInternational Journal of Innovation, 2015
Innovation is an increasingly relevant concept for the success of any organization, but it also represents a set of internal and external considerations, barriers and challenges to overcome.
Tiago João Freitas Correia   +2 more
doaj   +1 more source

Recognising and rewarding innovation in construction: exploring disconnections in managerial discourse [PDF]

open access: yes, 2009
The construction industry has often been considered a 'low innovation' sector. This research seeks to understand more deeply the manifestation of innovation at the construction workplace and raises questions as to whether there is really a dearth of ...
Chan, Paul, Littlemore, Michelle
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Innovation and new ways of working across sectors

open access: yesForced Migration Review, 2014
Humanitarian actors will have to adapt to a changing world but it will not be easy or straightforward. Operations are changing as a result of innovations which bring many improvements but also throw up challenges.
Erik Abild
doaj  

Innovation activities in Polish industry in 1998-2000: main results from the GUS 2001 innovation survey [PDF]

open access: yes, 2002
The paper analyses results of GUS innovation survey in manufacturing for 1998-2000 and innovation survey in services for 1997-1999. Innovation activities in 1998-2000 reflect downturn in Polish economy of this period.
Niedbalska, G.
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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