Results 61 to 70 of about 6,801,825 (368)
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Innovation and new ways of working across sectors
Forced Migration Review, 2014 Humanitarian actors will have to adapt to a changing world but it will not be easy or straightforward. Operations are changing as a result of innovations which bring many improvements but also throw up challenges.
Erik Abild
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Regional innovation case study review volume 2, 2007 - 2008 [PDF]
, 2007 A continuation of Volume 1, this 'Case Study Review' showcases a collection of case studies that represent the range of innovation support products and services available in the ...
East Midlands Innovation
core +1 more source
Unitary patent system and innovation dynamics in the European Union: The role of economic resources and R&D investments [PDF]
Journal of Entrepreneurship, Management and InnovationPURPOSE: The EU supports competitiveness and sustainability via innovations by the patent protection of inventions. On 1st June 2023, the EU launched the Unitary Patent System (UPS) with the Unitary Patent as a universal innovation protection tool.
Radka MacGregor Pelikánová +2 more
doaj +1 more source
Sticky Information and the Locus of Problem Solving: Implications for Innovation
, 1994 To solve a problem, needed information and problem-solving capabilities must be brought together. Often the information used in technical problem solving is costly to acquire, transfer, and use in a new location-is, in our terms, "sticky." In this paper ...
E. Hippel
semanticscholar +1 more source
Strategic Decisions, 2019 WHAT IF YOU COULD AMPLIFY HYDRAULIC FORCE WITHOUT ADDING ANY EXTRA BULK TO YOUR VEHICLE? A GROUNDBREAKING INNOVATION ENABLES YOU TO DO JUST THAT, HELPING TO IMPROVE THE OVERALL EFFECTIVENESS OF ANY ...
Paolo Fontana, J. P. Todsen
semanticscholar +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Resettlement and livelihoods innovation in the US
Forced Migration Review, 2014 Conversations with multiple stakeholders in the US help to highlight barriers to economic self-sufficiency for resettled refugees and opportunities for innovative approaches.
Faith Nibbs
doaj
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source