Results 31 to 40 of about 2,671,548 (302)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
SystemsIn response to intensifying environmental pressures and the rapid pace of digital transformation, firms are increasingly turning to artificial intelligence (AI) as a tool to support sustainable development.
Weiwei Wu, Xiaoxuan Wang
doaj +1 more source
Adopting and consuming innovations
Prometheus, 2010 This paper aims to improve understanding of how innovations are diffused through combining perspectives on the adoption and consumption of innovation. The literature on the adoption of innovation mainly examines issues such as technical functionalities ...
Ritsuko Ozaki, Mark Dodgson
doaj +1 more source
International Journal of Technology, 2023 Consumers' lack of trust in the private label brand is thought to be the root cause of private label's failure in developing markets, particularly in Asia. To improve their market share in developing markets, retailers must address private-label brand
Stany Wee Lian Fong +2 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
SOLL Platform and the Adoption of Innovation by Teachers
, 2021 The Internet of Things (IoT) appears with great educational potential, as it is a network composed of various objects and devices connected to the Internet, allowing the performance of interdisciplinary activities. Thus, we present the SOLL platform: Intelligent Objects Linked to Learning, which, supported by a set of technologies that collect and ...
Andreia Magalhães +2 more
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Adoption in the construction industry [PDF]
, 2006 This report draws together the key findings from six case studies on the subject of ebusiness\ud Adoption in Construction conducted in Australia by the University of Newcastle\ud (UON) and Royal Melbourne Institute of Technology (RMIT) from 2005 through ...
core
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source