Results 71 to 80 of about 2,671,548 (302)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Report of the Adoption Board 1993
, 1993 The Board received 529 applications for adoption orders in 1993. Applications for children being adopted within their natural family decreased from 296 in 1992 to 267 in 1993. These cases accounted for 50.5% of the applications received. Applications
Adoption Board
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
SAGE Open, 2014 The recent debate on innovation within an organizational setting has shifted focus toward discussing whether innovation is being adopted or being created.
Nor’Aini Yusof +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
The diffusion/adoption of innovation in the internal market [PDF]
The main aim of the present study is to analyze the drivers of innovation adoption by (i) developing proper measures able to proxy for innovation adoption and internal market regulations, (ii) identifying the channels through which innovation adoption ...
Fabio Manca +4 more
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Frontiers in CommunicationCommunication and innovation perception play interconnected roles in shaping farmers’ adoption of IoT-based smart farming technologies. This study examines how communication strategies and institutional support influence innovation perception and ...
Sumardjo +7 more
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
VikalpaTechnology innovation and adoption are key economic imperatives for growth in India’s economy, and especially in the healthcare sector. As an example of firm innovation adoption, this study explores the adoption of web accessibility standards by small ...
Krishna Jayakar, Smeeta Mishra
doaj +1 more source