Results 31 to 40 of about 142,966 (268)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Does Financial Resource Development Effort Affect the Dynamic Entrepreneurial Capability and Performance of SMEs?

Jurnal Manajemen Universitas Bung Hatta
The changes and uncertainty of the business environment in the VUCA era are serious challenges that must be faced, especially for SMEs. The unpreparedness of business actors to face these changes can impact the decline in SME performance and business ...
Liana Mangifera, Winny Perwithosuci, Siti Aisyah, Mega Wahyu Widawati   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The mediating role of innovation capability in efficiency of HCMC-based businesses

Tạp chí Phát triển và Hội nhập, 2023
The changes in the business environment and the increase in competition level have led organizations to focus on improving their operational efficiency.
Anh Tram Long Nguyen, Binh Thanh Ha Nguyen   +1 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

The Impact of Team Learning Climate on Innovation Performance – Mediating role of knowledge integration capability

Frontiers in Psychology, 2023
To address the fierce competition for corporate innovation in the digital economy, this study introduces knowledge integration capability as a mediating variable in light of social information processing theory, and explores the mechanism of team ...
Ming-Shun Li, Jiaqi Li, Jia-Mei Li, Zi-Wei Liu, Xin-Tao Deng   +4 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

From innovation capability to green innovation capability: Evidence from Chinese big tech firms

Journal of Economy and Technology
Innovation capability as a source of competitive advantage for firms is a consolidated topic in the literature. However, there is still little evidence about the green characteristics that innovation capability incorporates. This article aims to identify
Martín Hernani-Merino, Jorge Tello-Gamarra, David Mayorga, Julio Zevallos   +3 more
doaj   +1 more source

The Impacts of Technology Management on Product Innovation: The Role of Technological Capability

IEEE Access, 2020
Despite the growing importance of management practices, few studies have empirically examined the influence of technology management on product innovation, especially in the presence of technological capability.
Yexin Liu, Weiwei Wu, Yan Wang
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source