Results 101 to 110 of about 923,769 (294)
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Syahmida Syahbuddin Arsyad,1 Laili Rahayuwati,2 Rahmadewi,1 Septi Nurhayati,1 Arga Nugraha,3 Darojad Nurjono Agung Nugroho,4 Oktriyanto,1 Mugia Bayu Rahardja,1 Yanu Endar Prasetyo,1 Yanti Astrelina Purba,1 Ruth Meilianna,1 Indra Murty Surbakti,5 Wahyu ...
Syahbuddin Arsyad S +13 more
doaj
APPROACH OF RDI SYSTEM IN EUROPEAN UNION IN THE LAST DECADE [PDF]
Present paper present an approach of the Research-Development and Innovation System (RDI) in Europe during the last decade. After a short introduction is presented the European Union formation.
Nicolov Mirela, , ,
doaj
The Innovation Output Indicator 2019
This report presents the 2019 update of the Innovation Output Indicator (IOI), which is a composite indicator published every year by the European Commission since 2013 aiming to quantify the extent to which ideas for new products and services carry an economic added value and are capable of reaching the market. A novelty of this report is a special
VERTESY DANIEL, DAMIOLI GIACOMO
openaire +1 more source
Is Canada Really All That Bad At Innovation?: A Tale of Two Industries [PDF]
This commentary raises questions about the degree to which global innovation indicators enable us to understand the historical dynamics of innovation in Canada, and about future directions for Canadian innovation policy. By focusing on the automotive and
Richard Hawkins
core
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
The challenge of measuring innovation in emerging economies' firms: A proposal of a new set of indicators on innovation [PDF]
The traditional indicators on innovation rely on the linear assumption that research leads to development, centring on the measurement of inputs and outputs.
Marins, Luciana
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
INNOVATION AND COMPETITIVENESS [PDF]
This study, addresses the topic of industrial innovation in today's competitive markets and reaches the importance of competitiveness indicators. Any entrepreneurial attempt to produce and promote new and up-to-date products should be carried out ...
MARINCEAN Dan Andrei
doaj

