Results 41 to 50 of about 180,118 (263)
POMIAR INNOWACYJNOŚCI Z PERSPEKTYWY PRZEDSIĘBIORSTWA
Nowoczesne Systemy Zarządzania, 2017 Article describes different innovation indicators dedicated to product, process, organization and market innovation, measuring also efficiency and scope of the innovation process, expenditures on innovation, the benefits of innovation and cooperation in ...
PAWEŁ ŁUKASIK
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Measuring the Capacity of Organizations Innovation ‒ Major Process of Innovation Management
Amfiteatru Economic, 2015 The article approaches the problem of companies’ success in today’s economic context, characterized by a generalized market with increasing competitive and client requirements.
Dorin Maier +3 more
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Journal of Open Innovation: Technology, Market and Complexity, 2020 The innovative economy is based on effective interaction between the scientific and educational sphere and the business environment, free flow of innovative ideas, and active commercialization of developments in order to constantly update and develop the
Aleksandra Kobicheva +2 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Модернизация, инновация, развитие, 2015 On June 30, 2015 has come into force the Federal Law of theRussian Federation(№ 488-FL): “On the industrial Policy in theRussian Federation”. The law requires the innovation Production. At the same time, from the whole spectrum of the strategic documents
V. V. Simonova, O. O. Smirnova
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Innovation’s Performance: A Transnational Analysis Based on the Global Innovation Index
Administrative SciencesThe pandemic marked the beginning of a succession of events on a global scale (not the least of which is a greater concern for the environment and for quality of life/distance work) with a major impact on the economy.
Evelina Maria Oliveira Coutinho +1 more
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