Results 61 to 70 of about 181,588 (262)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Economic Innovation as a Mechanism to Activate Economic Development (Iraq is a Case Study)

open access: yesTikrit Journal of Administrative and Economic Sciences
The purpose of this paper is to importance of economic innovation in achieving economic development in Iraq, and reveal its role in building a society. It also develops a future vision to embrace economic innovation.
Sohaila Abdul Zahra Mastor Al-Hujaimi
doaj   +1 more source

Advanced materials foresight: research and innovation indicators related to advanced and smart nanomaterials. [PDF]

open access: yesF1000Res, 2022
Farcal L   +4 more
europepmc   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Innovation and growth: evidence from Latin American countries

open access: yesJournal of Applied Economics, 2019
This paper aims to analyze the relationship between innovation and per capita economic growth over the long-run for 12 Latin American countries for the period 1996–2015. This study uses six different indicators of innovation. Using Granger causality test,
Luis Alfredo Avila-Lopez   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

The challenge of measuring innovation types: A systematic literature review

open access: yesJournal of Innovation & Knowledge
Measuring innovation has long posed a significant challenge and has been the subject of extensive scientific research. Various definitions and measures of innovation exist, and each measurement approach faces limitations.
Alina Stundziene   +4 more
doaj   +1 more source

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