Results 91 to 100 of about 1,653,373 (307)
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
An innovation diffusion model of a local electricity network that is influenced by internal and external factors [PDF]
, 2017 Haynes et al. (1977) derived a nonlinear differential equation to determine the spread of innovations within a social network across space and time. This model depends upon the imitators and the innovators within the social system, where the imitators ...
Ablowitz +17 more
core +3 more sources
BMJ OpenObjectives To assess the feasibility and acceptability of delivering Healthy Eating and Active Lifestyles for Diabetes (HEAL-D) Online.Intervention HEAL-D Online—a 7-week culturally tailored type 2 diabetes educational programme delivered using online ...
Nick Sevdalis +7 more
doaj +1 more source
A large family of Dscam genes with tandemly arrayed 5′ cassettes in Chelicerata
Nature Communications, 2016 Drosophila Dscam1 and vertebrate clustered protocadherins (Pcdh) are known for their extraordinary isoform diversity. Here authors identify a shortened Dscam gene family in Chelicerata, which displays homology to Drosophila Dscam1, and employs splicing ...
Yuan Yue +11 more
doaj +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
A Dynamic Network Approach to Breakthrough Innovation
, 2012 This paper outlines a framework for the study of innovation that treats discoveries as additions to evolving networks. As inventions enter they expand or limit the reach of the ideas they build on by influencing how successive discoveries use those ideas.
Funk, Russell J., Owen-Smith, Jason
core +1 more source
Improving CPU Energy Efficiency for Low Latency Use Cases With Software-Defined Core Labeling
IEEE AccessIn this paper, we address the energy efficiency problems in general-purpose servers used for low-latency use cases. In use cases with strict latency requirements, power-saving features of Central Processing Unit (CPU) such as CPU idle are typically ...
Ko Natori, Ikuo Otani, Kei Fujimoto
doaj +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
The role of network ties in reaching radical innovation [PDF]
, 2018 The purpose of this paper is to analyze how institutions can facilitate or inhibit radical innovation. The authors maintain that organizational radical innovation is necessary to maintain a competitive advantage and evolve in the market place, and ...
Quero-Gervilla, Maria Jose +1 more
core
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source