Results 71 to 80 of about 750,727 (267)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Innovation Processes

, 2020
Research and innovation deployment requires skills and time. Innovation is a process that permits to companies and groups to adapt to social, economic and environmental changes. There are different approach to innovation. Some companies prefer to keep innovation place within the company boundaries, (closed innovation), meanwhile others companies have ...
Marco Vieri, Daniele Sarri, Stefania Lombardo, Marco Rimediotti, Riccardo Lisci, Valentina De Pascale, Eleonora Salvini, Carolina Perna, Andrea Pagliai   +8 more
openaire   +2 more sources

New Strategy for Microbial Corrosion Protection: Photocatalytic Antimicrobial Quantum Dots

Nanomaterials
Microbial corrosion has significant implications for the economy, environment, and human safety worldwide. Photocatalytic antibacterial technology, owing to its advantages in environmental protection, broad-spectrum, and efficient sterilization, presents
Shijia Liu, Dapeng Wu, Jie Zheng, Baochen Han, Jian Qi, Fanchun Meng, Jianhui Li, Dan Liu   +7 more
doaj   +1 more source

Successful application of the innovation process to a case of Floyd Type I tracheal agenesis. [PDF]

Surg Open Sci, 2023
Greene A, Zhang Y, Asan O, Clark JB, Fell B, Harter K, Samson T, Ravnic D, Cilley RE, Dillon P, Mackay D, Tsai AY.   +11 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Twitter as an innovation process with damping effect. [PDF]

Sci Rep, 2021
Aletti G, Crimaldi I.
europepmc   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Oil palm biomass ash removal for boiler fuel optimization: A case study

Case Studies in Chemical and Environmental Engineering
The growing demand for sustainable energy sources has prompted increased interest in biomass materials, particularly oil palm biomass (OPB), as an alternative to coal for power generation.
Herman Hidayat, Fausiah, Ahsonul Anam, Sudono, Erbert Ferdy Destian, Ilhamsyah Noor, Abdul Ghofar, Mochamad Rosjidi, Rudias Harmadi, Dorit Bayu Islam Nuswantoro, Aminuddin, Rudy Surya Sitorus, Dadang Rosadi, Muksin Saleh, Hariana, Trisaksono Bagus Priambodo, Iman, Umiati, Hadiyanto   +18 more
doaj   +1 more source

CONSUMER INVOLVEMENT IN THE VALUE CHAIN AS A MANAGEMENT INSTRUMENT OF INNOVATION PROCESSES IN A BISINESS ENVIRONMENT

Дискурс, 2018
The article discusses the trends in the innovation process management at the enterprise connected with the concept of "open innovation". The author shows the value-based approach role in the organization of innovative activity of the company.
T. N. Zhukova
doaj   +1 more source