Results 81 to 90 of about 750,727 (267)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Simultaneous Removal of SO2 and NOx Using Steel Slag Slurry Combined with Ozone Oxidation

open access: yesACS Omega, 2021
Xiaolong Liu   +4 more
doaj   +1 more source

Refining NaCl: Elevating Salt's quality from coarse to industrial and Pharmacy grade through innovative hydroextraction techniques

open access: yesCase Studies in Chemical and Environmental Engineering
Increased demand for industrial and pharmaceutical salt surpasses production capabilities, posing challenges for the salt industry. This study uses a cost-effective hydroextraction method utilizing mixing washers and hydrocyclone to enhance NaCl purity ...
Badrut Tamam Ibnu Ali   +7 more
doaj   +1 more source

IDENTIFICATION OF INNOVATION PROCESS ON NEW PRODUCT DEVELOPMENT IN SMALL AND MEDIUM ENTERPRISES

open access: yesJurnal Aplikasi Manajemen, 2019
Understanding the innovation process of new product development (NPD) is expected to support the company’s sustainability. This study aims to identify the NPD innovation process in the food and beverage industry in Indonesia.
Tommy C. Efrata   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Temperature-dependent deformation mechanisms and quantitative strength analysis of a Ni-based superalloy with bimodal precipitation distribution

open access: yesJournal of Materials Research and Technology
Ni-based superalloys are essential for high-temperature applications in aerospace, yet their mechanical properties are intricately linked to the size distribution of γ′ precipitations.
Qian Wang   +11 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Four Questions on Complexity and Learning [PDF]

open access: yesInterdisciplinary Description of Complex Systems, 2008
Increasing interaction (in numbers, patterns and uncertain intensity) in innovation processes point at new and different methodologies of researching reality including complexity views of modern production.
Miloš Pukl
doaj  

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