Results 31 to 40 of about 489,461 (263)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Transdisciplinary Research in the Built Environment: A Question of Time
Technology Innovation Management Review, 2018 In this article, we reflect on 14 years of experience with transdisciplinary research in the built environment. We critically consider challenges and pitfalls in relation to normative definitions of transdisciplinary research derived from the literature.
Paula Femenías, Liane Thuvander
doaj +1 more source
Underestimated Components of Infrastructure Support for Regional Innovation Processes in Ukraine [PDF]
Problemi Ekonomiki, 2019 The article focuses on the fact of underestimating engineering organizations in the regulatory framework and statistical accounting as an important component of infrastructure support for regional innovation processes.
Morhachov Illia V.
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Agricultural Economics (AGRICECON)In Spain, the leader in pesticide sales in the European Union, a high-tech and innovative company provides services to the wine industry to optimise phytosanitary work, reduce crop losses and lower production costs.
Raisa Pérez-Vas +3 more
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TASKS OF INNOVATION PROCESSES PROGRAM-TARGET MANAGEMENT AT REGIONAL LEVEL [PDF]
Krymskij Naučnyj Vestnik, 2015 The article analyzes the regional system of innovation management, discussed the existing problems of program-oriented management of innovative processes at the regional level, as well as possible solutions to improve the efficiency of the regional ...
Mikhail Shchepakin, Yuliya Tomilko
doaj
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source