Results 51 to 60 of about 489,461 (263)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Innovation Processes and Entrepreneurial Culture for Radical Innovations
Amfiteatru Economic, 2015 To survive and prosper, the organizations need to embed the processes and mechanisms to discover major technology and consumer trends and respond to them through new growth areas.
Ľubica Knošková
doaj
Geochemistry of Monazite within Carbonatite Related REE Deposits
Resources, 2017 Approximately >50% of global rare earth element (REE) resources are hosted by carbonatite related deposits, of which monazite is one of the most important REE minerals. Monazite dominates more than 30 carbonatite-related REE deposits around the world,
Wei Chen +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Development of a comprehensive framework to analyse systems of energy and environmental innovation [PDF]
بهبود مدیریت, 2019 Economic, social and technological changes with their impacts on environmental issues have received increasing notice in the years to come. The relationship between the historical approach of the development of technology and innovation processes will ...
Seyed Iman Miremadi +2 more
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2020 Research and innovation deployment requires skills and time. Innovation is a process that permits to companies and groups to adapt to social, economic and environmental changes. There are different approach to innovation. Some companies prefer to keep innovation place within the company boundaries, (closed innovation), meanwhile others companies have ...
Marco Vieri +8 more
openaire +2 more sources
Foreign experience of managing of economical innovative potential and the way of its using in Ukraine [PDF]
Marketing i Menedžment Innovacij, 2011 In this article theoretical aspects of innovation policy are researched. Also, the author specifically mentioned most effective instruments of inspiration of innovation activity in foreign countries and defined instruments of state innovation policy for ...
V.O. Kasianenko
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
PROFESSIONAL DEVELOPMENT OF MATHEMATICS TEACHERS
Высшее образование в России, 2016 The article presents the experience of course realization for professional development of Mathematics teachers organized in Tomsk State University of Control Systems and Radioelectronics (TUSUR).
Vyacheslav I. Efanov +2 more
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