Results 151 to 160 of about 1,908,628 (306)

Innovation network building in the Hungarian region of South Transdanubia [PDF]

open access: yes
The economic attraction of the regions depends on the spatially balanced network-based co-operation of different research bases, SMEs and organisations involved in innovation development these days.
Gál, Zoltán
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

The art and science of a strategic grantmaker: the experience of the Public Health Agency of Canada's Innovation Strategy. [PDF]

open access: yesCan J Public Health, 2021
Bradley Dexter S   +5 more
europepmc   +1 more source

Managing Search Strategies for Open Innovation: The Role of Environmental Munificence as well as Internal and External R&D [PDF]

open access: yes
Firms compete increasingly in an open innovation environment. Search strategies for external knowledge become therefore crucial for firm success. Existing research differentiates between the breadth (diversity) and depth (intensity) with which firms ...
Grimpe, Christoph, Sofka, Wolfgang
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

Company strategy: Business model reconfiguration for innovation and internationalization [PDF]

open access: yes
The competitiveness of a country is the result of the competitiveness of its firms. The competitiveness of firms is partly determined by how their business models interact with the environment to produce offerings with added value.
Casadesus-Massanell, Ramon   +1 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Evaluation of innovation activities of small and medium-sized businesses in Slovak Republic [PDF]

open access: yes
The aim of the presented paper is to contribute to the discussion on innovation activities of small and medium-sized businesses of the Slovak Republic and the European Union.
Kostiviarova, Silvia, Sopkova, Eva
core   +1 more source

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