Readiness for scale-up: lessons learned from the Public Health Agency of Canada's Innovation Strategy. [PDF]
Can J Public Health, 2021 Bradley Dexter S +5 more
europepmc +1 more source
Some Reflections on the Expert Panel Report on Business Innovation in Canada [PDF]
This article reviews the Council of Canadian Academies Expert Panel report on business innovation. It finds the report comprehensive in its gathering and assessment of available research, innovative, in its own right, in its analysis of innovation as an ...
Ian A. Stewart
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
Managing Search Strategies for Open Innovation: The Role of Environmental Munificence as well as Internal and External R&D [PDF]
Firms compete increasingly in an open innovation environment. Search strategies for external knowledge become therefore crucial for firm success. Existing research differentiates between the breadth (diversity) and depth (intensity) with which firms ...
Grimpe, Christoph, Sofka, Wolfgang
core
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
FEBS Open Bio, EarlyView.This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
The art and science of a strategic grantmaker: the experience of the Public Health Agency of Canada's Innovation Strategy. [PDF]
Can J Public Health, 2021 Bradley Dexter S +5 more
europepmc +1 more source
Looking for performance: how innovation and straregy may affect market orientation models [PDF]
Despite 20 years of research into various aspects of the ‘Market Orientation’ (MO) construct, dubiety persists regarding the existence, nature and significancy of the relationship between market orientation and firm performance.
Ana Fuster-Mur +3 more
core
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
Innovation Strategy Selection Facilitates High-Performance Flexible Piezoelectric Sensors. [PDF]
Sensors (Basel), 2020 Duan S, Wu J, Xia J, Lei W.
europepmc +1 more source