Results 41 to 50 of about 1,803,748 (309)
Role of Aortic Geometry on Stroke Propensity based on Simulations of Patient-Specific Models
Scientific Reports, 2017 Stroke is a life threatening event that is expected to more than double over the next 40 years. Atrial fibrillation (AF) has been reported as a strong independent risk factor for stroke.
Hyo Won Choi +3 more
doaj +1 more source
Exposure to acute noxious heat evokes a cardiorespiratory shock response in humans
International Journal of Hyperthermia, 2022 Background: Noxious acute cold stimuli cause cold shock via the sympathetic nervous system. However, no studies have investigated respiratory “heat shock” in response to noxious acute heat stimuli (≥ 42 °C).
Nerijus Eimantas +3 more
doaj +1 more source
How fast should we innovate? [PDF]
, 2013 The role of speed in innovations needs to be explored more thoroughly. I advocate here that for innovations which rely on scarce materials, research into more abundant substitutes needs to be accelerated while a regulatory ...
Vogt, Thomas
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Family Involvement in Management and Product Innovation: The Mediating Role of R&D Strategies [PDF]
, 2019 Following calls to capture family firms’ innovative behavior and to specifically clarify how family firms manage product innovations to achieve sustainable economic development, this study empirically investigates the mediating role of Research ...
Artz +46 more
core +3 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
SSTR2 as an anatomical imaging marker and a safety switch to monitor and manage CAR T cell toxicity
Scientific Reports, 2022 The ability to image adoptively transferred T cells in the body and to eliminate them to avoid toxicity will be vital for chimeric antigen receptor (CAR) T cell therapy, particularly against solid tumors with higher risk of off-tumor toxicity. Previously,
Yago Alcaina +4 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Bluetooth-Based Vehicle Counting: Bridging the Gap to Ground-Truth With Machine Learning
IEEE Access, 2023 Traffic flow, number of vehicles passing a particular point over a given period of time, is an essential indicator for evaluating the performance and condition of road networks, detecting congestion, and predicting traffic trends.
Fatima Tayeb +2 more
doaj +1 more source
ALPPS: Innovation for innovation's sake [PDF]
Surgery, 2016 HEPATIC RESECTION AND ABLATIVE PROCEDURES, which remain the mainstay treatment for patients with resectable colorectal liver metastases (CRLMs), can be facilitated by preoperative volumetric modulation when an insufficient liver remnant and/or diseased parenchyma are anticipated.
Jacques, Belghiti +2 more
openaire +2 more sources