Results 61 to 70 of about 1,855,001 (308)
BMC Medical Ethics, 2022 Background Sharing anonymized/de-identified clinical trial data and publishing research outcomes in scientific journals, or presenting them at conferences, is key to data-driven scientific exchange.
Friedrich Maritsch +6 more
doaj +1 more source
Work Organisation and Innovation [PDF]
, 2012 [Excerpt] Innovations in work organisation have the potential to optimise production processes in companies and improve employees’ overall experience of work.
Cox, Annette +2 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Eurolanguages-2010: Innovations and Development [PDF]
, 2010 Збірник наукових студентських робіт по підсумкам 8 Міжнародної конференції "Євромови ...
Аллахвердян, Тамара Миколаївна +8 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Comparison of personal and shared frameshift neoantigen vaccines in a mouse mammary cancer model
BMC Immunology, 2020 Background It is widely hoped that personal cancer vaccines will extend the number of patients benefiting from checkpoint and other immunotherapies. However, it is clear creating such vaccines will be challenging.
Milene Peterson +6 more
doaj +1 more source
SSTR2 as an anatomical imaging marker and a safety switch to monitor and manage CAR T cell toxicity
Scientific Reports, 2022 The ability to image adoptively transferred T cells in the body and to eliminate them to avoid toxicity will be vital for chimeric antigen receptor (CAR) T cell therapy, particularly against solid tumors with higher risk of off-tumor toxicity. Previously,
Yago Alcaina +4 more
doaj +1 more source
Classification and Impact of Innovations Launched by Czech Small and Medium-sized Enterprises [PDF]
, 2013 Purpose of the article: The article is focused on innovation activities that are considered a key element for future competitiveness of small and medium-sized enterprises.
Barton, Monika, Procházka, Lukáš
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
AnimalTo address multiple issues impacting the climate imbalance, insects, and in particular Tenebrio molitor, represent now a promising alternative for producing high-quality protein products with low environmental impact. As with any new species farmed on an
E. Sellem +7 more
doaj +1 more source