Results 41 to 50 of about 649,845 (314)

Role of Aortic Geometry on Stroke Propensity based on Simulations of Patient-Specific Models

Scientific Reports, 2017
Stroke is a life threatening event that is expected to more than double over the next 40 years. Atrial fibrillation (AF) has been reported as a strong independent risk factor for stroke.
Hyo Won Choi, Tong Luo, Jose A. Navia, Ghassan S. Kassab   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The Connecticut Innovations blog. 2013: Jul. [PDF]

, 2013
Irregular; Began with Sept.

core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Connecticut Innovations blog. 2012: Apr. [PDF]

, 2012
Irregular; Began with Sept.

core  

Aligning femtech innovation With equity: a strategic framework for real world impact

Frontiers in Global Women's Health
Femtech is advancing rapidly as a field with the capacity to transform women's health by addressing prevailing inequities in diagnosis, care, and access. Despite systemic, structural, cultural, data, regulatory, and access barriers that have historically
Shirin Ashrafganjouei, Lindsay Eziashi, Muskaan Bhan, Roswitha Priscilla Verwer, Melissa Paola Mezzari   +4 more
doaj   +1 more source

Author Correction: Prebiotic effects of yeast mannan, which selectively promotes Bacteroides thetaiotaomicron and Bacteroides ovatus in a human colonic microbiota model

Scientific Reports, 2021
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Shunsuke Oba, Tadahiro Sunagawa, Reiko Tanihiro, Kyoko Awashima, Hiroshi Sugiyama, Tetsuji Odani, Yasunori Nakamura, Akihiko Kondo, Daisuke Sasaki, Kengo Sasaki   +9 more
doaj   +1 more source

Clinical Performance of Cobas 6800 for the Detection of High-Risk Human Papillomavirus in Urine Samples

Vaccines, 2023
Testing for high-risk human papillomavirus (HPV) as part of primary cervical cancer screening has become more common recently. The Cobas 6800, an FDA-approved cervical screening platform, detects 14 high-risk HPVs, including HPV16 and HPV18.
Brian Joseph Hajjar, Ummar Raheel, Rachel Manina, Jovanie Simpson, Muhammad Irfan, Yasir Waheed   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Connecticut Innovations blog. 2012: Feb. [PDF]

, 2012
Irregular; Began with Sept.

core