Results 81 to 90 of about 1,855,001 (308)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Understanding Relationship: Maximizing the Effects of Science Coaching

open access: yesEducation Policy Analysis Archives, 2014
There is growing empirical evidence that instructional coaching can help teachers transfer their learning from professional trainings (e.g., new strategies) to classroom practice and that coaching promotes greater collaboration and reflection among ...
Ruth Anderson   +2 more
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Emergence and prospects of digital mediation in energy communities: ecosystem actors’ perspective

open access: yesEnergy, Sustainability and Society
Background Energy communities (ECs) hold out the promise of cleaner and more flexible energy systems through self-generation, demand response, and storage.
Khuram Shahzad   +3 more
doaj   +1 more source

Pricing under innovation [PDF]

open access: yes, 2018
We study pricing when firms introduce process and product innovations over time. We set up a model of endogenous productivity and markup under imperfect competition and dynamic pricing.
Jaumandreu, J., Lin, Shuheng
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Eurolanguages-2012: Innovations and Development [PDF]

open access: yes, 2012
Збірник наукових студентських робіт призначено для широкого кола читачів, які цікавляться проблемами вивчення іноземних мов та перекладу в ...
Алексеєв, Анатолій Якович   +14 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Quasi-firms for real innovations [PDF]

open access: yes, 1997
The construction industry is notorious for its (lack of) innovativeness. Many papers, reports\ud and articles have been written on this subject already for more than three decades.\ud The explanations presented can be summarized by such terms as ...
Dorée, A.G., Tongeren, H. van
core   +1 more source

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