Results 31 to 40 of about 484,838 (307)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Eco-friendly biopolymers and composites: a sustainable development of adsorbents for the removal of pollutants from wastewater

npj Materials Sustainability
Growing wastewater treatment demands drive reliance on polymeric materials to facilitate the process, and traditional fossil-based polymers face limitations, prompting the exploration of sustainable alternatives.
K. Mohanrasu, Arun Chandra Manivannan, Haryni Jayaradhika Raguraman Rengarajan, Raji Kandaiah, Akila Ravindran, Logeshwaran Panneerselvan, Thavamani Palanisami, C. I. Sathish   +7 more
doaj   +1 more source

Clustering as a component of economic institutional reforms (on the example of Siberian region) [PDF]

, 1998
The article gives the definition of the local cluster as a spatial and sectoral concentration of interconnected companies, the end product or service that is exported outside of the local territorial entity.
Flehmig, Folko, Marquardt, Wolfgang, von Watzdorf, Rüdiger   +2 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Disinfection impacts: Effects of different disinfection treatments on common polymer types to guide the identification of polymers of concern in the water industry

Cambridge Prisms: Plastics
Disinfection is a standard water treatment process. Plastics are found in various components of water infrastructure and the presence of microplastics in the water cycle raises environmental and human health concerns. Thus, this research investigated the
Kala Senathirajah, Raji Kandaiah, Logeshwaran Panneerselvan, Kyana Young, Thava Palanisami   +4 more
doaj   +1 more source

Top-Level Design and Simulated Performance of the First Portable CT-MR Scanner

IEEE Access, 2022
Multi-modality imaging hardware can be integrated in a single gantry to collect diverse datasets for complementary information and spatiotemporal correlation, with excellent examples including PET-CT and PET-MRI.
Yuting Peng, Mengzhou Li, Jace Grandinetti, Ge Wang, Xun Jia   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source