Results 31 to 40 of about 2,604,842 (296)
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Ученые записки Российской академии предпринимательства, 2022 The results of the analysis of Russian imports in various segments of the electrical products market are presented. It is shown that one of the ways to increase the level of competitiveness and ensure the import independence of enterprises for the ...
S. B. Moiseev, T. V. Kakatunova
doaj +1 more source
New understanding on the pearlite-induced brittle failure of bimetal composite interface
Materials & DesignThe pearlite–austenite interface is the primary cause of brittle failure of the Mn8/SS400 bimetal composite. Here, we present new microstructural understandings on this interfacial brittle failure.
Lisong Zhu +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
Mergers & acquisitions and innovation performance in the telecommunications equipment industry [PDF]
Industrial and Corporate Change, 2011 The worldwide telecommunications equipment industry has experienced an enormous number of mergers and acquisitions (M&A).
Tseveen Gantumur, Andreas Stephan
openaire +6 more sources
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Build your own equipment: Sustaining creative practice at home [PDF]
, 2022 In March 2020, the United Kingdom Covid-19 response created a huge challenge for the creative sector within higher education. With staff and students in lockdown, facilitating the study of practice-based subjects from home, without access to specialist ...
Lord, Jade, Sykes, Elinor
core
Synthetic CT generation for pelvic cases based on deep learning in multi-center datasets
Radiation OncologyBackground and purpose To investigate the feasibility of synthesizing computed tomography (CT) images from magnetic resonance (MR) images in multi-center datasets using generative adversarial networks (GANs) for rectal cancer MR-only radiotherapy ...
Xianan Li +10 more
doaj +1 more source
Comprehensive shape memory alloys constitutive models for engineering application
Materials & Design, 2023 The current shape memory alloys (SMA) constitutive models have the problems of complicated calculation, inaccurate results, measuring difficult parameters, and inconvenient application, which brings about challenges for designing, analyzing, and ...
Baiyan He +5 more
doaj +1 more source