Results 41 to 50 of about 2,604,842 (296)

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Macroporous polymer microspheres supported functional nanocrystals for efficient catalysis and antibacterial applications

Nano Research
Porous polymer-nanocrystals (NCs) organic-inorganic nanocomposites with integrated functions, enhanced stability, and controlled morphology are highly demanded across various fields due to their unique physicochemical properties.
Zhuyu Liu, Yan Wang, Jichun Li, Yue Sun, Meihua Chen, Xiu-Feng Hou, Yonghui Deng   +6 more
doaj   +1 more source

Protective Effects and Mechanism of Hyperoside in PC12 Cells Against Oxidative Stress Injury Induced by Hydrogen Peroxide

Natural Product Communications, 2021
As the aging phenomenon continues to increase, the incidence of neurodegenerative diseases continues to increase annually. As one of the significant contributive factors of neurodegenerative diseases, oxidative stress damage has received extensive ...
Yan Feng, Dongxu Wang, Qi Wang, Zhifeng Li, Shi-Lin Yang, Yu-Lin Feng, Tao Luo, Yan Li   +7 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Risk Mitigation Strategies for Operations and Maintenance Activities, Final Report; TR-627, April 2012 [PDF]

, 2012
The objective of this research was to investigate the application of integrated risk modeling to operations and maintenance activities, specifically moving operations, such as pavement testing, pavement marking, painting, snow removal, shoulder work ...

core  

Coupling 3D CFD of Air Knife Jets with an Analytical Model for Coating Thickness Prediction and Operating Window Definition in Hot-Dip Galvanizing

Eng
A coupled modeling framework is developed to predict coating thickness after air knife wiping in hot-dip galvanizing. A 3D large eddy simulation (LES) using the WALE sub-grid scale (SGS) model is performed to resolve the jet impingement on the moving ...
Hao Liu, Lisong Zhu, Muyuan Zhou, Daiyan Zhao, Di Pan, Haibo Xie, Jian Han, Hongwei Cao, Li Sun, Hongqiang Liu, Xi Wu, Tieling Zhang, Zhengyi Jiang   +12 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Developing Overall Equipment Effectiveness Metrics for Prototype Precision Manufacturing [PDF]

, 2011
Overall Equipment Effectiveness (OEE) is a powerful metric of manufacturing performance incorporating measures of the utilisation, yield and efficiency of a given process, machine or manufacturing line.
O\u27Neill, Michael, O'Neill, Michael, Michael, O'Neill   +2 more
core   +2 more sources

Chemical Fingerprint and Metabolic Profile Analysis of Tianshu Tablets by Ultra-High Performance Liquid Chromatography/Quadrupole-Time of Flight Mass Spectrometry

Journal of Analytical Methods in Chemistry, 2019
In recent years, the chemical fingerprinting of traditional Chinese medicines and the metabolites in these compounds has been a hot topic. In the present study, the chemical fingerprint of Tianshu tablets (TST) and the metabolic characteristics of ...
Lin Chen, Renhao Chen, Hui Ouyang, Qi Wang, Zhifeng Li, Yulin Feng, Shilin Yang   +6 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source