Results 71 to 80 of about 130,939 (260)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The impact of collaborative atmosphere on innovative work behavior of college teachers, North China

Frontiers in Psychology
Innovation and progress serve as the driving forces behind national development. Universities, with their comprehensive academic systems and robust research capabilities, undoubtedly play a crucial role in fostering student innovation and advancing ...
Qian Liu, Qian Liu, Yu Sun
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Behavioral Health Innovations during COVID in Black and Hispanic Communities

Journal for Social Action in Counseling and Psychology
In an effort to address behavioral health disparities, authors conducted a community engagement research study to identify innovative practices that behavioral health agencies utilized in Black and Hispanic communities during COVID-19.
Jennifer Baggerly, Samuel Bore, Constance Lacy, Corron Sanders, Erica Pouncie   +4 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Exploring challenges and innovation in memory assessment services in England and Wales – a national survey and case study approach

BMC Health Services Research
Background To explore the design, delivery models and identify good and innovative practices in Memory Assessment Services (MAS) in England and Wales.
Sarah Jane Smith, Claire Surr
doaj   +1 more source

Innovative Management Practices to Optimize Employee Performance [PDF]

Revista de Management Comparat International
The primary objective of this study is to identify and analyze innovative management practices that optimize employee performance in Romanian companies.
Sofia Mihaela ROMANESCU, Carmen Maria MIHALCEA, Denisa Mihaela ȘULĂ   +2 more
doaj   +1 more source

An Innovative Hybrid Neuro-wavelet Method for Reconstruction of Missing Data in Astronomical Photometric Surveys

, 2012
The investigation of solar-like oscillations for probing the star interiors has encountered a tremendous growth in the last decade. For ground based observations the most important difficulties in properly identifying the true oscillation frequencies of the stars are produced by the gaps in the observation time-series and the presence of atmospheric ...
CAPIZZI, GIACOMO, NAPOLI, CHRISTIAN, Paternò L.   +2 more
openaire   +3 more sources

Development of a New Innovative Teaching Method Using a Comprehensive Approach: A Survey of Students' Opinion [PDF]

Biomedical Journal of Scientific & Technical Research, 2018
Comprehensive teaching methods have been evaluated by many health professional colleges and universities for a number of years...
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source