Results 111 to 120 of about 2,535,717 (310)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Analysis of Taste and Differential Metabolites of Different Ganoderma lucidum Strains Based on Electronic Tongue and Non-targeted Metabolomics

Shipin gongye ke-ji
In order to explore the differences of taste and metabolites of different Ganoderma lucidum strains, the fruiting bodies of different Ganoderma lucidum strains were taken as samples, the taste of aqueous extracts of 21 different Ganoderma lucidum strains
Zhaoning HUANG, Shu LUO, Yi SONG, Zhou ZHOU, Liming HE, Yuan YANG, Xia LUO   +6 more
doaj   +1 more source

Exploring microRNA Signatures of DNA Damage Response Using an Innovative System of Genotoxic Stress in Medicago truncatula Seedlings. [PDF]

Front Plant Sci, 2021
Gualtieri C, Gianella M, Pagano A, Cadeddu T, Araújo S, Balestrazzi A, Macovei A.   +6 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Learning from the COVID-19 pandemic among migrants: An innovative, system-level, interdisciplinary approach is needed to improve public health. [PDF]

Scand J Public Health, 2021
Diaz E, Mamelund SE, Eid J, Aasen HS, Martin Kaarbøe O, Brokstad RJC, Gloppen S, Beyer A, Kumar BN.   +8 more
europepmc   +1 more source

Multi-user satellite communications system using an innovative compressive receiver [PDF]

There is a need for an onboard simultaneous multi-channel demodulation system for a satellite communications system. Studies indicate that Convolve Multiply Convolve (CMC) filtering with surface acoustic wave (SAW) dispersive delay lines will eliminate ...
Staples, Edward J.
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Developing an Innovative System of Open and Flexible, Patient-Family-Centered, Virtual Visiting in ICU During the COVID-19 Pandemic: A Collaboration of Staff, Patients, Families, and Technology Companies. [PDF]

J Intensive Care Med, 2021
Thomas KAS, O'Brien BF, Fryday AT, Robinson EC, Hales MJL, Karipidis S, Chadwick A, Fleming KJ, Davey-Quinn AP.   +8 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Airborne Dental Material Particulates and Occupational Exposure: Computational and Field Insights into Airflow Dynamics and Control Strategies

Toxics
Occupational exposure to airborne polymethacrylate (PMMA) particles during dental laboratory procedures poses an underexplored health risk. This study presents the first integrated Computational Fluid Dynamics (CFD) and real-time particle monitoring ...
Chanapat Chanbandit, Kanchana Kanchanatawewat, Ghaim Man Oo, Jatuporn Thongsri, Kuson Tuntiwong   +4 more
doaj   +1 more source