Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Production of Glycerol by Two Endogenic Wine Yeast Strains at Different Inoculum Size
In this study, effects of inoculum size on growth and batch glycerol production kinetics of two endogenic wine yeast strains Saccharomyces cerevisiae Kalecik 1 and Saccharomyces cerevisiae Narince 3 were investigated.
Seda Karasu Yalçin, Zekiye Yesim Özbas
doaj
Anaerobic biodigestion of sugarcane vinasse under mesophilic conditions using manure as inoculum
Sugarcane vinasse is one of the most polluting residues produced by Brazilian ethanol industries, mainly because of its harmful effects on the environmental, such as high organic matter load and acidity.
Carlos Eduardo de Farias Silva +1 more
doaj +1 more source
Two microbial strains Bacillus subtilis HDJ1 and Bacillus velezensis HDJ2 were screened from soybean paste samples by corn gluten meal medium for high protease activity.
REN Fei +4 more
doaj +1 more source
Evaluation of the effect of tyrothricin on beta-hemolytic streptococci in salva. Part I: The effect of salvia upon bacteria. Part II: Effect of tyrothricin on the New York 5 strain of Streptococcus pyogenes in saliva [PDF]
Part II of thesis by Brancato, Noyes, and Swift. Part I of thesis by Swift. Thesis (M.A.)--Boston UniversityThe antibacterial effect of saliva has been known for many years.
Brancato, Frank P. +2 more
core +1 more source
Impact of cereal rotation strategies on soil inoculum concentrations and wheat takeall
The fungus Gaeumannomyces graminis var tritici (Ggt) causes takeall in cereals and survives saprophytically on crop debris during the intercrop period Commercial wheat fields with different crop rotations on 10 farms in the South Island of New Zealand were monitored over 6 years for changes in Ggt inoculum concentrations and takeall severity Takeall ...
R.F. Van_Toor +4 more
openaire +2 more sources
Semeru Banana peel is an organic waste that is exclusively utilized as animal feed and does not harm the environment. The primary component of banana peels is carbohydrates, which can be used as a substrate during the fermentation process to produce lactic acid. The fermentation of banana peel flour with Lactobacillus plantarum strain FNCC 0020 was the
Abdullah Abdullah, Yufrida Amalia
openaire +2 more sources
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Kultur Campuran dan Faktor Lingkungan Mikroorganisme yang Berperan dalam Fermentasi âTea-Ciderâ
Tea is agricultural product containing beneficial substances, especially used for human health. The study of "Tea-cider" fermentation has been conducted using batch culture method.
Pingkan Aditiwati, Kusnadi Kusnadi
doaj +1 more source
1414. Inoculum Effect of Piperacillin/Tazobactam Concentration on Emergence of Resistance in Klebsiella aerogenes [PDF]
BACKGROUND: Piperacillin/tazobactam (PTZ) is a carbapenem-sparing option for AmpC-repressed organisms. Current strategies of dosing PTZ focus on prolonging fT > minimum inhibitory concentration (MIC), lowering C:MIC ratios. The objective of this study was to determine the effect of physiologic PTZ concentration on the emergence of resistance among ...
Custodio, Marco +5 more
openaire +1 more source

