Opuntia ficus‐indica fruit consumption improves insulin resistance in mice with diet‐induced obesity
Abstract BACKGROUND Obesity induces various co‐morbidities including insulin resistance. Opuntia ficus‐indica fruit (OFIF) is rich in various beneficial compounds with antioxidant and anti‐inflammatory properties. The present study evaluated the efficacy of OFIF supplementation to counteract obesity‐induced insulin resistance in comparison with an ...
Simona Terzo+9 more
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Targeting cannabinoid receptor 1 for antagonism in pro-fibrotic alveolar macrophages mitigates pulmonary fibrosis. [PDF]
Basu A+18 more
europepmc +1 more source
Abstract Background Peptic ulcers, particularly gastric ulcers (GUs), are multifactorial disorders with unclear mechanisms. Black garlic (BG) has shown gastroprotective effects. This study evaluated the effects of BG and epigallocatechin gallate‐impregnated BG (EG) in acidic ethanol (AE)‐induced GU model mice. Mice were pretreated with BG or EG (50–200
Ming‐Shiun Tsai+7 more
wiley +1 more source
The inhibition of TXNRD1 by methylglyoxal impairs the intracellular control of Mycobacterium tuberculosis. [PDF]
Li H+9 more
europepmc +1 more source
DNA Immunotherapy (INO‐3107) Results in Long‐Term Surgery Reduction in RRP
In a retrospective, observational extension study (RRP‐002) evaluating long‐term safety and clinical effect, DNA immunotherapy INO‐3107 was well tolerated and provided continued clinical effect against HPV‐6 and 11 recurrent respiratory papillomatosis (RRP) that resulted in further reduction of the surgical burden observed in Year 1. The mean number of
Milan R. Amin+15 more
wiley +1 more source
A Plant-Based Dietary Supplement Exhibits Significant Effects on Markers of Oxidative Stress, Inflammation, and Immune Response in Subjects Recovering from Respiratory Viral Infection: A Randomized, Double-Blind Clinical Study Using Vitamin C as a Positive Control. [PDF]
Fink B+6 more
europepmc +1 more source
Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti+4 more
wiley +1 more source
Immune cell diversity and regenerative markers reveal interactions among macrophages, rodlet cells, and stem cells in the kidney of Poecilia sphenops. [PDF]
Sayed RKA, Bakry M, Mokhtar DM.
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Protective Properties of the White Button Mushroom, Agaricus bisporus, in a Mouse Model of Colitis
In this study, whole mushroom powder (WMP) from white button mushrooms was tested for gut health benefits. In vitro digested WMP (IVD‐WMP) could reduce the permeability of a gastrointestinal cell layer. In mouse studies, WMP was tested as a preventative and a treatment for dextran sulfate sodium (DSS) induced colitis. WMP could improve recovery, reduce
Elaine Dempsey+5 more
wiley +1 more source
Suppression of LPS-Induced Inflammation by <i>Phragmites communis</i> Young Leaf Extract via Multi-Target Inhibition of IκB, AP-1, and STAT1/3 Pathways in RAW 264.7 Cells. [PDF]
Kang KY, Park KW.
europepmc +1 more source