The nuclear phosphoinositide-p53 signalosome in the regulation of cell motility. [PDF]
Hou X +10 more
europepmc +1 more source
KRN5b regulates maize kernel row number through mediating phosphoinositol signalling. [PDF]
Shen X +14 more
europepmc +1 more source
A novel regulator of the fungal phosphate starvation response revealed by transcriptional profiling and DNA affinity purification sequencing. [PDF]
Huberman LB +8 more
europepmc +1 more source
Dysregulation of Inositol Polyphosphate 5-Phosphatase OCRL in Alzheimer's Disease: Implications for Autophagy Dysfunction. [PDF]
Ando K +13 more
europepmc +1 more source
An Update on Polyphosphate In Vivo Activities. [PDF]
Schoeppe R +3 more
europepmc +1 more source
Plasma membrane and nuclear phosphatidylinositol 4,5-bisphosphate signalling in cancer. [PDF]
Chytła A +3 more
europepmc +1 more source
The diversity and possible functions of the inositol polyphosphate 5-phosphatases
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1998Distinct forms of inositol and phosphatidylinositol polyphosphate 5-phosphatases selectively remove the phosphate from the 5-position of the inositol ring from both soluble and lipid substrates, i.e., inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), inositol 1,3,4, 5-tetrakisphosphate (Ins(1,3,4,5)P4), phosphatidylinositol 4, 5-bisphosphate (PtdIns(4,5)P2)
Erneux, Christophe +3 more
openaire +4 more sources
The Structure and Function of Catalytic Domains Within Inositol Polyphosphate 5‐Phosphatases
IUBMB Life, 2002AbstractPhosphoinositide signaling pathways regulate many essential cellular functions including proliferation, differentiation and survival, cytoskeletal organization, and vesicular trafficking. The inositol polyphosphate 5‐phosphatases regulate the cellular levels of several bioactive phosphoinositide species.
J C, Whisstock +3 more
openaire +4 more sources
The family of inositol and phosphatidylinositol polyphosphate 5-phosphatases
Biochemical Society Transactions, 1996Introduction myo-Inositol-containing phospholipids form a minor, but metabolically highly active, component of eukaryotic membranes, where they play a central role in signal-transduction pathways. Hydrolysis of PtdIns(4,5)P2 by phospholipase C generates the two second messengers Ins( 1,4,5)P3 and diacylglycerol, which function in mobilization of ...
Drayer, Anneke Lyndsay +5 more
openaire +2 more sources
The SH2 domain containing inositol polyphosphate 5-phosphatase-2: SHIP2
The International Journal of Biochemistry & Cell Biology, 2005Phosphoinositides are membrane-bound signaling molecules that recruit, activate and localize target effectors to intracellular membranes regulating apoptosis, cell proliferation, insulin signaling and membrane trafficking. The SH2 domain containing inositol polyphosphate 5-phosphatase-2 (SHIP2) hydrolyzes phosphatidylinositol 3,4,5-trisphosphate ...
Jennifer M, Dyson +5 more
openaire +2 more sources

