Results 91 to 100 of about 17,550 (284)

Inotropes in the beta-blocker era [PDF]

Clinical Cardiology, 2000
Beta-adrenergic blocking agents are now standard treatment for mild to moderate chronic heart failure (CHF). However, although many subjects improve on beta blockade, others do not, and some may even deteriorate. Even when subjects improve on beta blockade, they may subsequently decompensate and need acute treatment with a positive inotropic agent.
Brian D. Lowes, Tatiana Tsvetkova, Michael R. Bristow, Marc A. Simon   +3 more
openaire   +3 more sources

Safety and efficacy of up to 60 h of iv istaroxime in pre‐cardiogenic shock patients: Design of the SEISMiC trial

ESC Heart Failure
Aims Cardiogenic shock (CS) is linked to high morbidity and mortality rates, posing a challenge for clinicians. Interventions to improve tissue perfusion and blood pressure are crucial to prevent further deterioration.
Jan Biegus, Alexander Mebazaa, Marco Metra, Matteo Pagnesi, Ovidiu Chioncel, Beth Davison, Gerasimos Filippatos, Agnieszka Tycińska, Maria Novosadova, Gaurav Gulati, Marianela Barros, Maria Luz Diaz, Carlos Guardia, Robert Zymliński, Piotr Gajewski, Piotr Ponikowski, Phillip Simmons, Steven Simonson, Gad Cotter   +18 more
doaj   +1 more source

Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome: results of an international survey [PDF]

, 2014
Background: Surveys have demonstrated a lack of physician awareness of intra-abdominal hypertension and abdominal compartment syndrome (IAH/ACS) and wide variations in the management of these conditions, with many intensive care units (ICUs) reporting ...
De Keulenaer, Bart L, De laet, Inneke, De Waele, Jan, Debergh, Dieter, Kirkpatrick, Andrew W, Malbrain, Manu LNG, Roberts, Derek J, Vandervelden, Stefanie, Wise, Robert   +8 more
core   +1 more source

Two causes of COVID‐19‐related myocardial injury‐associated cardiogenic shock: Myocarditis and microvascular thrombosis

ESC Heart Failure, Volume 12, Issue 2, Page 1514-1522, April 2025.
Takamasa Iwai, Hirohiko Aikawa, Yoshiaki Morita, Keiko Ohta‐Ogo, Teruo Noguchi   +4 more
wiley   +1 more source

Current and novel biomarkers in cardiogenic shock

European Journal of Heart Failure, EarlyView.
A summary of current and novel biomarkers and their potential stages of release in cardiogenic shock. The diagram illustrates the proposed release of the biomarkers during the different stages of cardiogenic shock: progression from cardiac dysfunction/stress, through to inflammation and end‐organ dysfunction.
Victor Galusko, Florian A. Wenzl, Christophe Vandenbriele, Vasileios Panoulas, Thomas F. Lüscher, Diana A. Gorog   +5 more
wiley   +1 more source

Successful use of levosimendan as a primary inotrope in pediatric cardiac surgery: An observational study in 110 patients

Annals of Pediatric Cardiology, 2016
Context: Levosimendan is a new generation inotrope with calcium sensitizing properties and proven benefits in adults. Aims: This study investigates the use of levosimendan as a first line inotrope in congenital heart surgery.
Reena Khantwal Joshi, Neeraj Aggarwal, Mridul Aggarwal, Rakesh Pandey, Veronique Dinand, Raja Joshi   +5 more
doaj   +1 more source

Effect of a Perioperative, Cardiac Output-Guided Hemodynamic Therapy Algorithm on Outcomes Following Major Gastrointestinal Surgery A Randomized Clinical Trial and Systematic Review [PDF]

, 2014
Importance: small trials suggest that postoperative outcomes may be improved by the use of cardiac output monitoring to guide administration of intravenous fluid and inotropic drugs as part of a hemodynamic therapy algorithm.Objective: to evaluate the ...
Abdy, Sue, Ackland, Gareth, Ahern, Aoife, Ahmad, Tahania, Antonelli, Jean, Baldwin, Jackie, Baytug, Beki, Beale, Richard, Beardow, Zoe, Beattie, Craig, Beatty, Monika, Bellingan, Geoff, Bennett, David, Berridge, John, Berry, William, Birch, Sian, Blunt, Mark, Bodger, Phoebe, Bolger, Clare, Boyd, Owen, Breen, Andrew, Cameron, David, Carter, Joseph, Carvalho, Peter, Chikhani, Marc, Clarkson, Rachel, Clements, Debbie, Coats, Tim, Corlett, Sarah, Cottam, Simon, Cronin, James, Dark, Paul, Daugherty, Mark, Dickinson, Matt, Dunsire, Fraser, Elliot, Stuart, Evley, Rachel, Fawcett, Erik, Gallego, Laura, Gates, Simon, Gent, Emma, Gibson, John, Gillies, Michael, Gillies, Michael A., Grice, Alex, Griffiths, Karen, Griggs, Kathryn, Grocott, Michael, Grocott, Michael P.W., Hadfield, Daniel, Harrison, David A., Harvey, Sheila, Hay, Alasdair, Hellewell, Alastair, Hester, Natalie, Hinds, Charles, Hinton, Lisa, Hobbinger, Helen, Hope, David, Howell, Simon, Hutchings, Melanie, Irvine, Michael, Januszewska, Marta, Johnston, Darryl, Jonas, Max, Jones, Chris, Kelliher, Lee, Kershaw, Melanie, Kirk-Bayley, Justin, Kunst, Gudrun, Lei, Katie, Linford, Karen, Lobo, Dileep, MacDonald, Neil, Maddison, Ben, McAlees, Eleanor, McAuley, Danny, McCulloch, Corienne, McKenzie, Cathy, McKeown, Dermot, McNeela, Fiona, Milner, Helen, Mohr, Otto, Moondi, Parvez, Moppett, Iain, Mullenheim, Jost, Niebrzegowska, Edyta, Ostermann, Marlies, Owen, Tom, Parks, Rowan, Parnell, Wendy, Parsons, Georgina, Peach, Jennifer, Pearce, Adrian, Pearse, Rupert, Pearse, Rupert M., Piper, Jess, Pittman, James, Potter, Alison, Pretorius, Robert, Price, Robert, Redman, Jonathan, Reyes, Anna, Reynolds, Toby, Rice, Leslie, Rowan, Kathryn, Sanderson, Barnaby, Scott, Rachael, Shafeek, Sherif, Shankar, Shiny, Smith, Amanda, Smith, John, Smolen, Sue, Sothisrihari, Saranga, Steel, Alistair, Stephens, Rob, Stubbs, Clare, Swan, Karen, Tan, Jermaine, Taylor, Gail, Topliffe, Joanne, Treasure, Tom, Tricklebank, Stephen, Wade-Smith, Fiona, Walsh, Angela, Walsh, Timothy, Wan, Ruth, Watson, Beverley, Wijewardena, Gayathri, Williams, Sarah, Wilson, Elizabeth, Wilson, Jonathan, Wolf, Rebecca, Wong, Kate, Wright, Chris, Yates, David, Young, Ben, Young, Neil, Young, Peter   +138 more
core   +1 more source

Registries on transcatheter edge‐to‐edge repair in heart failure: Current evidence and future perspectives

European Journal of Heart Failure, EarlyView.
Clinical evidence in transcatheter edge‐to‐edge valve repair. EF, ejection fraction; eGFR, estimated glomerular filtration rate; EROA, effective regurgitant orifice area; GDMT, guideline‐directed medical therapy; HF, heart failure; HHF, hospitalization for heart failure; LVEDV, left ventricular end‐diastolic volume; MR, mitral regurgitation; MVARC ...
Gianluigi Savarese, Christian Basile, Marianna Adamo, Stefan D. Anker, Antoni Bayes‐Genis, Michael Böhm, Erwan Donal, Gerasimos S. Filippatos, Francesco Maisano, Piotr Ponikowski, Giuseppe M.C. Rosano, Ralph Stephan von Bardeleben, Marco Metra, Javed Butler   +13 more
wiley   +1 more source

Micellized Naringenin Augments Hemodynamics After Myocardial Infarction by Suppressing Tubulin Detyrosination

Applied Sciences
Impaired contractility after myocardial infarction (MI) causes cardiogenic shock. MARK4 activity impairs contractility post-MI by increasing α-tubulin detyrosination.
Noah Weingarten, Amit Iyengar, Jessica Dominic, Danika Meldrum, Andrew Belec, Sara Guevara-Plunkett, Rachel Wilson, Joyce Ho, Mrinal Patel, Chaitanya Karimanasseri, Ahmad Amirshaghaghi, Daphne Nie, Benjamin W. Lee, Deborah M. Eaton, Kenneth B. Margulies, Zhiliang Cheng, Andrew Tsourkas, Pavan Atluri   +17 more
doaj   +1 more source

Rapid Estimation of Left Ventricular Contractility with a Physics-Informed Neural Network Inverse Modeling Approach [PDF]

Physics-based computer models based on numerical solution of the governing equations generally cannot make rapid predictions, which in turn, limits their applications in the clinic. To address this issue, we developed a physics-informed neural network (PINN) model that encodes the physics of a closed-loop blood circulation system embedding a left ...
arxiv   +1 more source