Troponin T as myocardial ischemia marker to guide therapy with positive inotropes in septic shock patients [PDF]
, 1997 OV Hein +8 more
openalex +1 more source
Refractory septic shock in children: a European Society of Paediatric and Neonatal Intensive Care definition [PDF]
, 2016 PURPOSE: Although overall paediatric septic shock mortality is decreasing, refractory septic shock (RSS) is still associated with high mortality. A definition for RSS is urgently needed to facilitate earlier identification and treatment.
Benissa, MR +14 more
core
Predicting Surfactant Need at Birth: Failed Validation of a Bedside Method Using Gastric Aspirates
Acta Paediatrica, EarlyView.ABSTRACT Aim To validate a prototype point‐of‐care (POC) test for the lecithin/sphingomyelin (L/S) ratio by identifying the optimal L/S cut‐off for predicting surfactant need in preterm infants < 30 weeks' gestation using gastric aspirates (GAS) sampled at birth and to assess clinical feasibility.
Christian Heiring +9 more
wiley +1 more source
Automatic motion estimation with applicationsto hiPSC-CMs [PDF]
arXivHuman induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are an effective tool for studying cardiac function and disease, and hold promise for screening drug effects on human tissue. Changes to motion patterns in these cells are one of the important features to be characterized to understand how an introduced drug or disease may alter the
arxiv
Photolysis of the novel inotropes EMD 57033 and EMD 57439: evidence that Ca2+sensitization and phosphodiesterase inhibition depend upon the same enantiomeric site [PDF]
, 1996 John A. Lee +2 more
openalex +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Dobutamine is a first‐line therapy for hypotension in anaesthetised horses, but the effects on haemodynamic parameters in standing and anaesthetised horses are not well studied. Objectives To investigate the effects of dobutamine in escalating dosages on haemodynamic performance in awake and anaesthetised horses.
Emma B. Gorenberg +4 more
wiley +1 more source
Influence of cellular mechano-calcium feedback in numerical models of cardiac electromechanics [PDF]
arXivMultiphysics and multiscale mathematical models enable the non-invasive study of cardiac function. These models often rely on simplifying assumptions that neglect certain biophysical processes to balance fidelity and computational cost. In this work, we propose an eikonal-based framework that incorporates mechano-calcium feedback -- the effect of ...
arxiv
Rationale for the use of drugs in the treatment of cardiovascular disease 3. Positive inotropes [PDF]
, 1999 Adrian Boswood
openalex +1 more source
Internal Medicine Journal, Volume 55, Issue 4, Page 645-654, April 2025.Abstract Background and Aims Ward‐delivered non‐invasive respiratory supports (NIRS) (conventional oxygen therapy (COT), high‐flow nasal oxygen (HFNO), continuous positive airway pressure (CPAP) and non‐invasive ventilation (NIV)), are often used to treat hospitalised patients with acute respiratory failure (ARF) both in high acuity and general wards ...
Catherine Buchan +4 more
wiley +1 more source