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Inotropic actions of eicosanoids
Basic Research in Cardiology, 1992Eicosanoids (prostaglandins, leukotrienes, thromboxane A2 and other metabolites of C-20 polyunsaturated fatty acids) have numerous effects in the cardiovascular system. Direct inotropic actions have been repeatedly described, but appear in only very few cases to be due to direct modification of the inotropic state of the heart.
Karsten Schrör, Th. Hohlfeld
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2011
Medication errors and adverse drug events occur more frequently in the intensive care unit compared to general care units.1 Adverse drug events become more likely as patients receive more medications. Sentinel events and medication errors are more common as the number of failing organs increases.2,3 Vasopressors are frequently associated with adverse ...
Scott W. Mueller, Robert MacLaren
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Medication errors and adverse drug events occur more frequently in the intensive care unit compared to general care units.1 Adverse drug events become more likely as patients receive more medications. Sentinel events and medication errors are more common as the number of failing organs increases.2,3 Vasopressors are frequently associated with adverse ...
Scott W. Mueller, Robert MacLaren
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Anaesthesia & Intensive Care Medicine, 2021
Shailendra K. Motwani, Helen Saunders
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Shailendra K. Motwani, Helen Saunders
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An Overview of Inotropic Agents
Seminars in Cardiothoracic and Vascular Anesthesia, 2006The use of inotropic agents has been surrounded by many controversies. Recent guidelines for the treatment of patients with chronic and acute heart failure have elucidated some of the issues, but many remain. As a result, a substantial variability in the use of agents between institutions and caregivers remains, which mainly results from the lack of ...
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ChemInform Abstract: Inotropic Activities of Imidazopyridines.
ChemInform, 1990AbstractA series of 2âarylimidazopyridines such as (III), (VI), and (VIII) is prepared by different cyclocondensation methods outlined in the reaction scheme.
V.P. Gerskowitch +12 more
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Amrinone: Is it the inotrope of choice?
Journal of Cardiothoracic Anesthesia, 1989In the treatment of acute heart failure, conventional therapy with epinephrine, norepinephrine, dopamine, and dobutamine may be used effectively to treat inotropic abnormalities. However, the addition of a vasodilator to catecholamine therapy may be needed to help improve lusitropic function.
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Paediatrics and Child Health, 2009
Critically ill children with shock frequently require the administration of inotropic and vasoactive agents. The appropriate choice of inotropic agent in these children forms only part of their overall management. In most cases children requiring inotropes should already have received aggressive fluid resuscitation and prompt tracheal intubation and ...
Fauzia Paize, Stephen D. Playfor
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Critically ill children with shock frequently require the administration of inotropic and vasoactive agents. The appropriate choice of inotropic agent in these children forms only part of their overall management. In most cases children requiring inotropes should already have received aggressive fluid resuscitation and prompt tracheal intubation and ...
Fauzia Paize, Stephen D. Playfor
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2016
Vasopressor and inotropic agents have become a therapeutic cornerstone for the management of the critically ill patient. Vasopressors increase blood pressure through arteriolar vasoconstriction, whereas the inotropes increase contractility, improving cardiac output. Most vasopressor and inotropic agents in clinical use exert their cardiovascular effect
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Vasopressor and inotropic agents have become a therapeutic cornerstone for the management of the critically ill patient. Vasopressors increase blood pressure through arteriolar vasoconstriction, whereas the inotropes increase contractility, improving cardiac output. Most vasopressor and inotropic agents in clinical use exert their cardiovascular effect
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Inotropes and Vasopressors for Shock
DeckerMed Critical Care of the Surgical Patient, 2019Inotropes and vasopressors play a key role in the management of shock. The goal of therapy is to restore end-organ perfusion by augmenting cardiac output (CO) and vascular tone. Clinical trial data have thus far failed to identify precise hemodynamic end points associated with better outcomes; in any event, such end points are highly likely to be ...
Gareth L. Ackland, Amour Patel
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Sympathomimetics, Inotropics, and Vasodilators
AACN Advanced Critical Care, 1992Management of the critically ill patient often necessitates the use of multiple inotropic and vasoactive medications. This article offers a concise, clinical reference to guide the practicing clinician in the use of these agents. The focus is on parenteral agents used for acute rather than chronic management. Physiologic concepts basic to understanding
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