Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala+6 more
wiley +1 more source
Low cardiac output syndrome after cardiac surgery: A retrospective analysis
Low cardiac output syndrome is a prevalent complication observed after cardiac surgery, related to elevated rates of mortality and morbidity. The study aimed to pinpoint independent risk factors for low cardiac output through the analysis of post-cardiac
I. Bechri+3 more
doaj +1 more source
Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients The ROADMAP Study 2-Year Results [PDF]
OBJECTIVES The authors sought to provide the pre-specified primary endpoint of the ROADMAP (Risk Assessment and Comparative Effectiveness of Left Ventricular Assist Device and Medical Management in Ambulatory Heart Failure Patients) trial at 2 years ...
Boyle, Andrew J.+15 more
core +2 more sources
Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants. [PDF]
ObjectiveTo analyze reasons for low enrollment in a randomized controlled trial (RCT) of the effect of hydrocortisone for cardiovascular insufficiency on survival without neurodevelopmental impairment (NDI) in term/late preterm newborns.Study designThe ...
A Das+26 more
core +1 more source
Modulation of the cardiomyocyte contraction inside a hydrostatic pressure bioreactor: $\textit{in vitro}$ verification of the Frank-Starling law [PDF]
We have studied beating mouse cardiac syncytia $\textit{in vitro}$ in order to assess the inotropic, ergotropic, and chronotropic effects of both increasing and decreasing hydrostatic pressures. In particular, we have performed an image processing analysis to evaluate the kinematics and the dynamics of those pressure-loaded beating syncytia starting ...
arxiv +1 more source
Multicenter Validation of the Vasoactive-Ventilation-Renal Score as a Predictor of Prolonged Mechanical Ventilation After Neonatal Cardiac Surgery [PDF]
Objectives: We sought to validate the Vasoactive-Ventilation-Renal score, a novel disease severity index, as a predictor of outcome in a multicenter cohort of neonates who underwent cardiac surgery. Design: Retrospective chart review.
Cashen, Katherine+7 more
core +1 more source
Vasopressors and inotropes in cardiogenic shock patients: an analysis of the MIMIC-IV database
IntroductionPharmacological support has become the mainstay therapy in patients with cardiogenic shock (CS). Unfortunately, the clinical benefits of such potent drugs remain unclear, therefore, the present study aims to elucidate the safety and efficacy ...
Bryan Richard Sasmita+2 more
doaj +1 more source
Preoperative and perioperative use of levosimendan in cardiac surgery: European expert opinion [PDF]
In cardiac surgery, postoperative low cardiac output has been shown to correlate with increased rates of organ failure and mortality. Catecholamines have been the standard therapy for many years, although they carry substantial risk for adverse cardiac ...
A., Eremenko+26 more
core +1 more source
Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial [PDF]
Introduction Congenital heart disease (CHD) is a major cause of infant mortality. Many infants with CHD require corrective surgery with most operations requiring cardiopulmonary bypass (CPB).
+19 more
core +3 more sources
Levosimendan for the prevention of acute organ dysfunction in sepsis [PDF]
BACKGROUND Levosimendan is a calcium-sensitizing drug with inotropic and other properties that may improve outcomes in patients with sepsis. METHODS We conducted a double-blind, randomized clinical trial to investigate whether levosimendan reduces the ...
Al-Beidh, F+16 more
core +2 more sources