Primary Cardiac Allograft Dysfunction-Validation of a Clinical Definition [PDF]
Background.Heart transplantation is an established treatment for advanced heart failure. Primary allograft dysfunction (PGD) is reported in up to 40 % of transplants and is associated with a poor outcome.Methods.As part of Heart Evaluation and Retrieval ...
Banner, Nicholas R +2 more
core +2 more sources
Study protocol: NITric oxide during cardiopulmonary bypass to improve Recovery in Infants with Congenital heart defects (NITRIC trial): a randomised controlled trial [PDF]
Introduction Congenital heart disease (CHD) is a major cause of infant mortality. Many infants with CHD require corrective surgery with most operations requiring cardiopulmonary bypass (CPB).
+19 more
core +3 more sources
Commentum to "Levosimendan for the Prevention of Acute Organ Dysfunction in ...
Morelli, Andrea, Tritapepe, Luigi
core +1 more source
Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome: results of an international survey [PDF]
Background: Surveys have demonstrated a lack of physician awareness of intra-abdominal hypertension and abdominal compartment syndrome (IAH/ACS) and wide variations in the management of these conditions, with many intensive care units (ICUs) reporting ...
De Keulenaer, Bart L +8 more
core +1 more source
Increased Long-Term Mortality among Black CABG Patients Receiving Preoperative Inotropic Agents [PDF]
The aim of this study was to examine racial differences in long-term mortality after coronary artery bypass grafting (CABG), stratified by preoperative use of inotropic agents. Black and white patients who required preoperative inotropic support prior to
Alan Kypson +18 more
core +2 more sources
Current use of inotropes in circulatory shock
Background Treatment decisions on critically ill patients with circulatory shock lack consensus. In an international survey, we aimed to evaluate the indications, current practice, and therapeutic goals of inotrope therapy in the treatment of patients ...
Thomas W. L. Scheeren +42 more
doaj +1 more source
Myocardial depressant effects of interleukin 6 in meningococcal sepsis are regulated by p38 mitogen-activated protein kinase [PDF]
Our findings demonstrate an integral role of the p38 mitogen-activated protein kinase pathway in interleukin 6-mediated cardiac contractile dysfunction and inotrope insensitivity.
Abraham +68 more
core +1 more source
Cardiovascular drug therapy for human newborn: review of pharmacodynamic data [PDF]
BACKGROUND: Circulatory failure in preterm and term newborn infants is commonly treated with inotropes or vasoactive medications. In this structured literature review, the available data on pharmacodynamic effects of the inotropes adrenaline ...
Bravo, MC +5 more
core +1 more source
Blood pressure intervention levels in preterm infants : pilot randomised trial [PDF]
OBJECTIVE: To examine the feasibility of a trial allocating different blood pressure (BP) intervention levels for treatment in extremely preterm infants.
Kempley, Stephen T. +5 more
core +1 more source
Incidence, management, and outcomes of cardiovascular insufficiency in critically ill term and late preterm newborn infants [PDF]
OBJECTIVE: The objective of this study was to characterize the incidence, management, and short-term outcomes of cardiovascular insufficiency (CVI) in mechanically ventilated newborns, evaluating four separate prespecified definitions. STUDY DESIGN:
Backstrom Lacy, Conra +22 more
core +1 more source

