Results 121 to 130 of about 18,495 (200)

Modulation of the PI3K/AKT/mTOR and AMPK/TSC2/mTOR Pathways by N-Acetyl-L-Cysteine as a Protector of Embryonic Bodies from the Toxic Effect of Methylmercury. [PDF]

Brain Sci
Simões JLB, Braga GC, Assmann CE, Bagatini MD.   +3 more
europepmc   +1 more source

Gamma SARS‐CoV‐2 variant of concern infection repercussions on pregnancy outcomes: A translational cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study conduct viral genome sequencing among severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)‐infected pregnant and postpartum individuals, and investigates disease severity and maternal and perinatal outcomes considering variant of concern (VOC) and non‐VOC groups.
Guilherme M. Nobrega, Fabiana Granja, Mariene R. Amorim, Luciana S. Mofatto, Daniel A. Toledo‐Teixeira, Julia Forato, Priscilla P. Barbosa, Jose Paulo S. Guida, Adriana G. Luz, Giuliane J. Lajos, Carolina C. Ribeiro‐do‐Valle, Gisele A. Pedroso, Kamila C. S. Krywacz, Angelica Z. Schreiber, Giuliana D. Moreno, Rodrigo N. Angerami, Maria Luiza Moretti, Rodolfo C. Pacagnella, Renato T. Souza, Jose Guilherme Cecatti, Rodrigo G. Stabeli, Magnun N. N. Santos, Fernando R. Spilki, Ester C. Sabino, Nuno R. Faria, William M. de Souza, Jose Luiz Proenca‐Modena, Maria Laura Costa   +27 more
wiley   +1 more source

Oropouche fever cases in Salvador, Bahia, Brazil, 2024. [PDF]

Braz J Infect Dis
Miranda A, Costa RJ, Ticona JPA, Brites C, Wang WK, Netto EM, Centro de Pesquisa, Aprendizagem e Inovação ‒ Fundação José Silveira.   +7 more
europepmc   +1 more source

Developing a social vulnerability index for antenatal care screening of risk for adverse maternal and perinatal outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Social determinants of health influence maternal and perinatal outcomes, yet tools to operationalize these risks in clinical care remain scarce. We aimed to study social determinants in Brazilian pregnant women and develop a social vulnerability index (SVI) that could correlate with pregnancy and perinatal outcomes.
Gabriel Q. Rippel, Renato T. Souza, Jussara Mayrink, Maria J. Miele, Rafael B. Galvao, Maria L. Costa, Francisco E. Feitosa, Edilberto A. Rocha Filho, Debora F. Leite, Ricardo P. Tedesco, Danielly S. Santana, Karayna G. Fernandes, Janete Vettorazzi, Iracema M. Calderon, Jose G. Cecatti   +14 more
wiley   +1 more source

Telehealth as a Strategy to Expand Access in Brazil's Unified Health System: Analysis of São Paulo State's Experience Across the Three Levels of Health Care. [PDF]

JMIR Form Res
Buto MSS, Carvalho GB, Garcia ML, de Andrade MCCLB, de Lima RR, Cerri GG, Carvalho CRR.   +6 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos, Matheus Cavalcanti de Barros, Cleidiane Silva Vieira de Souza, Ryan Cristian da Silva, Luana Cassandra Breitenbach Barroso Coelho, Maria Tereza dos Santos Correia, Fernanda das Chagas Ângelo Mendes Tenório, Alisson Macário de Oliveira, Thiago Henrique Napoleão, Robson Raion de Vasconcelos Alves, Patrícia Maria Guedes Paiva   +10 more
wiley   +1 more source

Fungicidal Activity and In Silico Studies of Triazoles Derived From Glycerol Against Neocosmospora falciformis, A Causal Agent of Guava Tree Decline. [PDF]

Chem Biodivers
Costa AV, Correia AO, Benvindo Dos Anjos B, de Oliveira MB, Gazolla PAR, de Queiroz VT, Resende JA, Teixeira RR, de Oliveira OV, Vargas GJ, Júnior WCJ, Moraes WB, Alves FR.   +12 more
europepmc   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Melanoma Cells Exposed to Clomiphene Citrate Respond With Cell Cycle Arrest and Reduced Invasiveness

Journal of Applied Toxicology, EarlyView.
ABSTRACT Epidemiological studies have suggested that clomiphene citrate (CC) exposure may increase the risk of malignant melanoma, but mechanisms are unknown. We investigated the effects of CC on melanoma cell line A375. Cells were treated with CC at 2, 20, 200, and 2000 ng/mL, followed by assessment of cell viability and metabolism, cell cycle ...
Thaís S. Ribeiro, Felipe H. S. Silva, Ana Paula G. S. Miranda, Isabella T. Borges, Pedro H. D. M. Prazeres, Marcia C. F. Ferreira, Enio Ferreira, Fernando M. Reis, Helen L. Del Puerto   +8 more
wiley   +1 more source