Results 221 to 230 of about 431,919 (294)

Fenfluramine in SCN1A‐related GEFS+: A multicenter observational study on efficacy, EEG improvement, and tolerability

open access: yesEpilepsia Open, EarlyView.
Abstract The SCN1A gene is implicated in a broad spectrum of epilepsy phenotypes, ranging from self‐limited genetic epilepsy with febrile seizures plus (GEFS+) to severe developmental and epileptic encephalopathies such as Dravet syndrome (DS). While fenfluramine (FFA) has demonstrated strong efficacy in DS, its role in SCN1A‐related epilepsies beyond ...
Giovanni B. Dell'Isola   +12 more
wiley   +1 more source

Evaluating the task‐specificity model of verbal memory: Regional volumetric analyses in temporal lobe epilepsy with hippocampal sclerosis

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Verbal memory tasks differ in their cognitive demands and may rely on distinct left medial temporal structures. One model holds that verbal delayed recall is hippocampal dependent, whereas verbal paired associate learning relies on adjacent rhinal cortex.
Andy Sitoh   +7 more
wiley   +1 more source

Sudden unexpected death in epilepsy (SUDEP): Risk management of pediatric patients with epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death in people with epilepsy with an incidence of 1:1000. The primary risk factors for SUDEP are generalized or focal to bilateral tonic–clonic seizures. Preventive measures like nighttime monitoring devices and resuscitation training address modifiable risk factors.
Laura Lutz   +3 more
wiley   +1 more source

What does it mean to live with epilepsy? Burden of illness from the patient perspective

open access: yesEpilepsia Open, EarlyView.
Our web based survey explored the real world experiences of patients with epilepsy (PwE) taking antiseizure medications (ASMs) who continue to have at least one seizure per month. The graphical abstract summarizes the study population, survey methodology, and key outcomes.
Joanne M. Wagner   +6 more
wiley   +1 more source

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