Results 61 to 70 of about 502,539 (201)

The emission benefits of European integration

open access: yesEnvironmental Research Letters, 2019
Simulating the implications of Brexit on the UK’s emissions embodied in trade with a multi-region input–output table exposes the benefits of European integration. Under 2014 trade volumes, technologies and energy mixes, a hard Brexit—reverting to a trade
Luís Costa, Vincent Moreau
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Impacto económico de los hoteles: aplicación en la ciudad de Sevilla [PDF]

open access: yesPASOS Revista de Turismo y Patrimonio Cultural, 2010
nowadays there is a growing interest in quantifying the economic impact generated by some productive industries or economic activities on the national, regional or local economy.
Miryam González Limón
doaj  

Regional Economic Growth Disparities in Ukraine: Input-Output Analysis Approach

open access: yesScientific Annals of Economics and Business, 2017
Regional inequalities in economic growth had been observed within many countries and regions. This research emphasizes convergence/divergence technique for Ukrainian regions.
Hryhorkiv Vasyl   +3 more
doaj   +1 more source

Recent evolution of wine exports in a turbulence period: a multiregional input-output analysis. [PDF]

open access: yesAgric Food Econ, 2023
Carrasco I   +3 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Pilot Appliacation of the Dynamic Input-Output Model. Case Study of the Czech Republic 2005-2013 [PDF]

open access: yesStatistika: Statistics and Economy Journal, 2016
The aim of this article is to provide the very first analysis in the field of dynamic Input-Output (I-O) models for the Czech Republic. This study examines the practicality of production dynamic equations for an estimation of future production enhanced ...
Karel Šafr
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

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