Results 81 to 90 of about 4,892,007 (362)

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

An inquiry into the productivity of the Indian pharmaceutical industry: application of data envelopment analysis

open access: yesBrazilian Journal of Operations & Production Management, 2017
Pharmaceutical industry is an important and significant industry in India. The common practice by experts, would-be investors and stakeholders of a pharmaceutical firm is to observe the year-end or quarterly financial figures of a firm and then use them ...
umang gupta kumar gupta, rohit kapoor
doaj   +1 more source

Fast metabolite identification with Input Output Kernel Regression

open access: yesBioinform., 2016
Motivation: An important problematic of metabolomics is to identify metabolites using tandem mass spectrometry data. Machine learning methods have been proposed recently to solve this problem by predicting molecular fingerprint vectors and matching these
Céline Brouard   +5 more
semanticscholar   +1 more source

An HEI-disaggregated input-output table for Wales [PDF]

open access: yes, 2010
This paper describes how the education sector of the Welsh Input-Output tables is disaggregated to identify a separate sector for each of Wales’s twelve Higher Education Institutions (HEIs).
Hermannsson, Kristinn   +3 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Research into the methods of analysing the productivity indicators of transport terminals [PDF]

open access: yesTransport, 2009
The measurement of terminal productivity is the issue of extreme importance to both terminal owners and management and customers. As the sector of transport is highly intensive in terms of investments into the infrastructure, the productivity of a ...
I. Jaržemskienė
doaj   +2 more sources

Evaluasi program pelaksanaan kelas ibu balita di wilayah kerja dinas kesehatan kabupaten banjarnegara

open access: yesJunal Kebidanan Dan Keperawatan Aisyiyah, 2018
Penelitian ini bertujuan untuk mengetahui evaluasi pelaksanaan kelas ibu balita di wilayah kerja Dinas Kesehatan Kabupaten Banjarnegara. Metode penelitian deskriptif dengan pendekatan cross sectional. Rancangan penelitian observasi dan wawancara.
Lia Aria Ratmawati
doaj   +1 more source

Home - About - Disclaimer - Privacy