Results 41 to 50 of about 52,175 (253)

Learning Nonlinear Motor Control: How Integrating Machine Learning and Nonlinear Dynamics Reveals Structure, Adaptation, and Control in Human Movement

Actuators
Human movement emerges from complex interactions between neural processes, musculoskeletal dynamics, and environmental constraints, resulting in behavior that is inherently nonlinear.
Armin Hakkak Moghadam Torbati, Yavar Shiravand, Armin Mazinani   +2 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Workload control: Successful implementation taking a contingency-based view of production planning & control [PDF]

, 2013
Purpose – The purpose of this paper is to present a successful implementation of a comprehensive workload control (WLC) concept; and to describe the associated implementation process.
Stevenson, Mark, Hendry, Linda, Huang, Yuan   +2 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

A Data‐Driven Control Framework for HIV Infection Using Projection Recurrent Neural Networks and Singular Value Analysis

Engineering Reports
In this study, we explore drug treatment for HIV infection through a novel approach that combines data‐driven sliding mode control (DDSMC) with a projection recurrent neural network (PRNN).
Ashkan Zarghami, Mehdi Siahi, Fereidoun Nowshiravan Rahatabad   +2 more
doaj   +1 more source

Robust Closed–Open Loop Iterative Learning Control for MIMO Discrete-Time Linear Systems with Dual-Varying Dynamics and Nonrepetitive Uncertainties

Mathematics
Iterative learning control (ILC) typically requires strict repeatability in initial states, trajectory length, external disturbances, and system dynamics. However, these assumptions are often difficult to fully satisfy in practical applications.
Yawen Zhang, Yunshan Wei, Zuxin Ye, Shilin Liu, Hao Chen, Yuangao Yan, Junhong Chen   +6 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Static output-feedback stabilization of discrete-time Markovian jump linear systems: a system augmentation approach [PDF]

, 2010
This paper studies the static output-feedback (SOF) stabilization problem for discrete-time Markovian jump systems from a novel perspective. The closed-loop system is represented in a system augmentation form, in which input and gain-output matrices are ...
Lam, James, Xiong, J, Xiong, Junlin, Shu, Z, Lam, J, Shu, Zhan   +5 more
core   +1 more source

Drivers of Carbon Emissions in China’s Construction Industry: A Perspective from Interregional Carbon Transfer

Buildings
The construction sector is pivotal to China’s economy, with interregional trade driving carbon emission transfers. This study uses 2007–2017 panel data from 30 provinces to analyze provincial carbon transfer patterns, combining input-output analysis and ...
Wenwen Xiao, Wenhao Song, Xuemei Pei, Lili Wang   +3 more
doaj   +1 more source