Results 51 to 60 of about 837,485 (313)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Training Neural Networks Using Input Data Characteristics
Advances in Electrical and Computer Engineering, 2008 Feature selection is often an essential data processing step prior to applying a learning algorithm. The aim of this paper consists in trying to discover whether removal of irrelevant and redundant information improves the performance of neural network ...
CERNAZANU, C.
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Simulation study of analog input buffer characteristics for low-voltage operation in CMOS integrated circuits [PDF]
, 2009 P(論文)Complementary-type analog input buffer is proposed for low-voltage operation in CMOS integratedcircuits. It consists of a conventional source-follower and an inverter-type input buffer.
ホリキ, ユウト +5 more
core +1 more source
Input variable selection in time-critical knowledge integration applications: A review, analysis, and recommendation paper [PDF]
, 2013 This is the post-print version of the final paper published in Advanced Engineering Informatics. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Tavakoli, S, Poslad, S, Mousavi, A
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Small-signal input characteristics of step-down and step-up converters in various conduction modes [PDF]
, 2016 Small-signal input characteristics of BUCK and BOOST DC-DC power converters in continuous conduction and discontinuous conduction mode have been presented. Special attention is paid to characteristics in discontinuous conduction mode.
Janke, W., Walczak, M.
core +1 more source
Biostimulants’ influence on tomato fruit characteristics at conventional and low-input NPK regime
Acta Agriculturae Scandinavica. Section B, Soil and Plant Science, 2020 Plant biostimulants are commercial products based on different chemical substances used to enhance plant growth and productivity. The effects of biostimulants, Megafol and Viva, with different dominant compositions (amino acids and humic acids) on two ...
Izudin Klokić +5 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Role of input weighting and bounding in the characteristic GPC method
International Journal of Control, 1990 Transcribing the Characteristic decomposition of a transfer function matrix of a discrete-time multivariable system from the frequency domain to the time domain provides a convenient means of breaking down complex multivariable GPC problems into a set of simple scalar Characteristic Generalized Predictive Control (GPC) problems.
Kouvaritakis, B, Rossiter, J
openaire +2 more sources