Results 71 to 80 of about 837,485 (313)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Analysis of the input power flow characteristics of cylindrical shells with combination boundaries
Journal of Low Frequency Noise, Vibration and Active Control, 2019 In this study, the input power flow problem of the cylindrical shell with complex acoustic boundaries was investigated. According to the acoustic characteristic of control domain which combination free interface and rigid wall interface at the same time ...
Luyun Chen, Yong Liu
doaj +1 more source
Dependence of output on input in DES: Small avalanche characteristics [PDF]
, 2007 New general properties in the S-boxes were found. Techniques and theorems are presented which allow to evaluate the non-substitution effect in f and the key clustering in DES. Examples are given. Its importance related to the security of DES is discussed.
Yvo Desmedt +2 more
openaire +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Neural learning for articulatory speech synthesis under different statistical characteristics of acoustic input patterns [PDF]
, 2003 Input data representation is highly decisive in neural learning in terms of convergence. In this paper, within an analytical and statistical framework, the effect of the distribution characteristics of the input pattern vectors on the performance of the ...
Altun, H, Yalcinoz, T, Curtis, KM
core +1 more source
CALCULATION OF INPUT-OUTPUT CHARACTERISTICS OF POWER UNITS UNDER INCOMPLETE INFORMATION [PDF]
Oil Shale, 2022 Heiki Tammoja, R. Attikas, J. Shuvalova
doaj +1 more source
Proposal for objective evaluation criteria for steering feel by steering torque sinusoidal input
Nihon Kikai Gakkai ronbunshu, 2017 The steering feel is an important technical problem for handling and drivability of driver-vehicle system and various kinds of studies have been conducted.
Ikuo KUSHIRO, Keisuke SUZUKI
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source