Results 81 to 90 of about 762,412 (265)

Modification of Computer-Aided Modelling Input Data Based on Medium-Scale Fire Tests of Wooden Beams

BioResources
The aim of the paper was to optimize the settings of the material properties of a computer model describing heat transfer in a wooden beam exposed to thermal loading from a porcelain radiation panel.
Dominik Spilak, Katarina Dubravska, Andrea Majlingova, Cong Jin, Qiang Xu, Lin Jiang   +5 more
doaj  

Caregiver Language Input in Different Engagement States During Play Interactions With Toddlers With Autism: An Observational Study

Autism and Developmental Language Impairments
Caregiver language input is a key component of children's early developmental environment, with its nature likely varying based on certain characteristics.
Yijie Li, Shaoli Lv, Linru Liu, Leran Xue, Huishi Huang, Yu Xing, Qianying Ye, Feixia Zhang, Hongzhu Deng   +8 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Examining the effect of farm and farmers' characteristics and input allocation on potato production

Frontiers in Sustainable Food Systems
The objective of this research was to examine the effects of farm and farmers' characteristics, and input allocation on potato production in Gowa Regency, South Sulawesi Province, Indonesia, using binary logistic regression.
Ardi Rumallang, Ardi Rumallang, Muslim Salam, Letty Fudjaja, Pipi Diansari, Baharuddin Patandjengi, Rahim Darma, A. Nixia Tenriawaru, Heliawaty, Akhsan, Rahmadanih, Rida Akzar, Muhammad Ridwan, Hamed Noralla Bakheet Ali   +13 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Input random processes of chemical-engineering objects simulation

Тонкие химические технологии, 2006
It is revealed, that consideration of chemical-engineering objects’ random components of input and output characteristics enables to determine more subtle characteristics of their operation.
V. I. Bozhko
doaj  

STATIONARY STOCHASTIC INPUT FLOW MODELING OF BRANCHED CONVEYOR SYSTEMS

Сучасні інформаційні системи
The object of research is stochastic stationary input material flow of a conveyor-type transport system. Subject of research is a method for generating realizations of a stationary stochastic input flow of material on the basis of experimental data. The
Oleh Pihnastyi , Victoriya Usik , Anna Burduk   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source