Results 51 to 60 of about 2,590,076 (294)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Determination of the relationship between outputs and inputs in agriculture in the EU member states

Agricultural and Resource Economics, 2017
The EU member states have established FADN (The Farm Accountancy Data Network) system to collect and process accounting data from agricultural holdings. The system is based on precisely defined methodology that is unique for all member states.
Aleksandra Figurek, Una Vasković
doaj  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Input-output analysis of Vietnamese structural changes (1989-1995)

East Asian Economic Review, 1999
The pattern and sequencing of economic reform in transition economies have become a major issue of interest since the late 1980s. While Eastern Europe and especially the Soviet Union have experienced difficulties in their transition to a market-based ...
Yul Kwon
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Applying Multilevel Models to the Input-Output Analysis

مجله اقتصاد و توسعه کشاورزی, 2015
In the present study, an application of multilevel modeling approach to the input- output analysis are presented First, the regional input-output table of all provinces in Iran was extracted based on the Adjusted Flegg Location Quotient Method (AFLQ ...
Fateme Hayatgheibi, M. Ghorbani
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Output frequency response function-based analysis for nonlinear Volterra systems [PDF]

, 2007
Analysis of nonlinear systems has been studied extensively. Based on some recently developed results, a new systematic approach to the analysis of nonlinear Volterra systems in the frequency domain is proposed in this paper, which provides a novel ...
Bendat, Billings, Boyd, Chen, Elizalde, Engelberg, Graham, Jing, Jing, Kim, Lang, Lang, Nam, Nuij, Petkovska, Peyton Jones, Peyton Jones, Rugh, Sandberg, Sandberg, Sandberg, Sandberg, Sanders, Stephen A. Billings, Taylor, Volterra, Xing Jian Jing, Yue, Yue, Zi Qiang Lang   +29 more
core   +1 more source

Grey enterprise input–output analysis

Journal of Computational and Applied Mathematics, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Li, Qiao-Xing, Liu, Si-Feng, Lin, Yi
openaire   +2 more sources