Results 181 to 190 of about 95,295 (264)

The DOAC‐FRAIL Study—Same Dose, Different Story: Prevalence of Deviant Direct Oral Anticoagulant Levels in Nursing Home Residents

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are prescribed using fixed dosing regimens, despite limited evidence on their pharmacokinetic behavior in nursing home residents. Participants and Setting One hundred nursing home residents are receiving apixaban, rivaroxaban, dabigatran, or edoxaban in multiple long‐term care facilities in the ...
Irme S. Franssen, Melanie J. de Jong, Lars Visseren, Daan Teerds, Dave Hellenbrand, Yvonne Henskens, Henri Spronk, Daisy J. A. Janssen, Dionne C. W. Braeken, Sander M. J. van Kuijk, Kristien Winckers, Fabienne J. H. Magdelijns   +11 more
wiley   +1 more source

Bilevel Optimized Implicit Neural Representation for Scan-Specific Accelerated MRI Reconstruction. [PDF]

IEEE Trans Med Imaging
Yu H, Fessler JA, Jiang Y.
europepmc   +1 more source

Plant cis‐regulatory grammar: Decoding the multidimensional code of transcriptional regulation for programmable crop engineering

Journal of Integrative Plant Biology, EarlyView.
This review decodes the grammar of plant cis‐regulatory elements, revealing that their function emerges from sequence, chromatin accessibility, 3D topology, and cell type context. It highlights how single‐cell omics, CRISPR dissection, and AI‐driven design converge to enable predictive engineering and crop improvement. ABSTRACT Cis‐regulatory elements (
Libin Zhang, Maoteng Li
wiley   +1 more source

Physiological Phenotypes in Comatose ICU Patients: A Retrospective Multidimensional Analysis. [PDF]

Diagnostics (Basel)
Bogdan PM, Pleșea-Condratovici A, Bogdan-Goroftei RE, Duceac LD, Armencia AO, Dabija MG, Salim C, Dabija VA, Nicolcescu P, Cristescu-Budală CL, Barbu ER, Calin AM.   +11 more
europepmc   +1 more source

Overwhelming Post‐Splenectomy Sepsis From Capnocytophaga canimorsus

International Journal of Laboratory Hematology, EarlyView.
Maitlyn Hsia, Maud Ahmad, Cyrus C. Hsia, Benjamin Chin‐Yee   +3 more
wiley   +1 more source

Retrospective evaluation of outcomes in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban as a sole or adjunctive thromboprophylaxis agent: 34 cases (2018‐2024)

Journal of Small Animal Practice, EarlyView.
Objectives To describe clinical outcomes, thromboembolic and haemorrhagic complications, and treatment characteristics in dogs with non‐associative immune‐mediated haemolytic anaemia treated with rivaroxaban at a UK referral hospital. Materials and Methods Retrospective descriptive study of dogs diagnosed with non‐associative immune‐mediated haemolytic
S. Conway, L. Jenkins, J. Reeve
wiley   +1 more source

The Liver as a Biomarker Organ in Heart Failure: Molecular Mechanisms, Hepatic Scores and Systemic Risk Stratification. [PDF]

Int J Mol Sci
Szczurek-Wasilewicz W, Borowiec A, Waluszewska I, Szyguła-Jurkiewicz B.   +3 more
europepmc   +1 more source

Oral Soft Tissue Biopsy in Patients Receiving Direct Oral Anticoagulants: A Prospective Cohort Study on Bleeding Outcomes

Oral Diseases, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) are the first‐line therapy for stroke prevention in non‐valvular atrial fibrillation and venous thromboembolism. While evidence supports their continuation during routine dental procedures such as tooth extractions, data on oral soft tissue biopsies remain limited.
Rossana Izzetti, Chiara Cinquini, Antonio Barone, Marco Nisi   +3 more
wiley   +1 more source

Prediction model for hypertrophied liver volume followed by hemihepatectomy: a retrospective cohort study. [PDF]

Ann Surg Treat Res
Yu J, Park S, Choi GS, Kim J, Oh N, Kim B, Rhu J.   +6 more
europepmc   +1 more source

Pharmacogenomics in Dentistry: From CYP‐Mediated Drug Response to Precision Prescribing in Oral Healthcare

Oral Diseases, EarlyView.
ABSTRACT Objective This narrative review critically assesses the clinical relevance of pharmacogenomics within dental genomics, distinguishing clinically actionable applications from emerging or investigational findings. Materials and Methods A targeted literature review was conducted in PubMed/MEDLINE, Scopus and Embase for publications from January ...
Giorgia Pieretto, Jessica Cusato, Martina Sansavini, Christian Bacci   +3 more
wiley   +1 more source